Words similar to resorbed

Example sentences for: resorbed

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The measurement of CTX isoforms, and the ratios between the native α Lform and the age-modified forms of CTX, indicative of the age of the resorbed collagen fragments, may thus provide clinical useful information for diagnosing and monitoring bone metastasis occurrence in cancer patients [ 11 ] . Such an application of the CTX bone resorption markers may be especially relevant for breast cancer patients, who have a high risk of developing bone metastases.
It has been shown that in Paget's disease of bone, a condition characterised by a localised upregulation of bone turnover, there is a significant increase in the ratio between the native peptide form of CTX (α L) and the age-modified forms (β L, D-isoaspartyl peptide and α D) [ 9 ] . The use of CTX ratios may thus be indicative of the significant decrease in the residence time and therefore the average age of the resorbed bone collagen type I fragments in Pagetic patients [ 9 ] . This indicates that perturbations in the normally well-regulated process of bone turnover can result in changes in the half-life of collagen type I within the bone matrix.
More 'young bone' (as reflected by the α LCTX levels) will be resorbed and the relative content of age-modified forms will decrease.
As described by Hofbauer et al [ 24], the quantity of bone resorbed depends on the balance between expression of RANKL and of its inhibitor, osteoprotegerin (OPG).