Words similar to repress
Example sentences for: repress
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Several lines of evidence indicate that NF-κB is constitutively activated in cancer cells, suggesting that it plays an important role in tumorigenesis [ 30 ] . Activated glucocorticoid receptors have been shown to repress NF-κB-mediated gene expression [ 31 ] , and to cause a significant reduction in nuclear levels of p65 protein, a subunit of NF-κB [ 31 ] . A variety of mitogens, cytokines, and reactive oxygen intermediates have been shown to rapidly cause the translocation of NF-κB to the nucleus [ 30 31 32 ] , and the ability of dexamethasone to interfere with this translocation is blocked by prior treatment with the glucocorticoid antagonist RU 486 [ 30 ] . Based on these findings, it is plausible to speculate that exposure to RU 486 may interfere with the function of endogenous glucocorticoids as regulators of cell cycle, allowing the initiation and progression of malignant transformation of liver cells.
In addition, Nrg1 and Ssn6 interact with each other in two-hybrid and GST pull-down assays, indicating that Nrg1 may repress via the same pathway as Mig1.
Increasing sugar levels have been shown to repress expression of alpha-amylases in rice seedlings [ 24 ] and suspension culture cells [ 25 ] . Studies using barley embryos provide evidence for the existence of independent glucose and disaccharide signaling mechanisms in the regulation of alpha-amylase expression [ 26 ] . Sugar regulation of alpha-amylase expression has also been shown to occur at multiple levels.
Besides inhibiting proteasome activity, the peptide aldehyde proteasome inhibitors have been also reported to repress certain lysosomal cysteine proteases and calpains [ 49 ] . The finding that MG-132 can obstruct the casein degrading activity of the calcium-dependent protease calpain [ 50 ] appears relevant to oocyte maturation.
Blotted coat proteins were visualized using anti-MS2 serum and 125I-protein A. The relative in vivo RNA binding activities of the various mutants are reflected in their abilities to repress translation of a replicase-β-galactosidase fusion expressed from pRZ5 in E. coli strain CSH41F -[ 6].