Example sentences for: repress

How can you use “repress” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As noted above, CORT/GR binding both activates specific gene expression and transrepresses NF-κB [ 47 ] . To repress NF-κB, the GR associates through protein-protein interactions with NF-κB bound at κB response elements [ 44 45 46 47 ] . The precise relationship between decreased NF-κB-mediated transcription and a decreased GR protein expression is unclear.

  • Additionally, the sar1Δ crosses were grown on glucose to repress the plasmid borne copy of GAL-SAR1 .

  • For example, transcription factor 8 (TCF8) can repress interleukin 2 (IL2) expression by binding to a negative regulatory element 100 bp upstream of the IL2 transcription start site [ 15].

  • Mig1's activity is regulated by phosphorylation and subcellular localization: in high glucose, Mig1 protein is hypophosphorylated and in the nucleus, where it can repress transcription; upon withdrawal of glucose, Mig1 is rapidly phosphorylated and transported into the cytoplasm [ 9].

  • Other NR coactivators include TRAP220 [ 7 ] , which is part of a larger complex (TRAP/DRIP/SMCC/mediator) that contacts the basal transcription machinery and PGC-1 [ 8 ] , a cold inducible coactivator that binds CBP and SRC-1 and proteins involved in RNA processing [ 9 ] . NR corepressors include NR corepressor (N-CoR) and silencing mediator of retinoid and thyroid responsive transcription (SMRT) [ 4 ] . Both N-CoR and SMRT repress transcription, at least in part, by binding to histone de-acetylases (HDACs) either directly or indirectly through other corepressor complex components.


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