Example sentences for: remodelling

How can you use “remodelling” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • S. cerevisiae SWI/SNF [ 3 ] , Ino80 complex [ 4 ] , Drosophila NURF [ 5 ] are examples of some high molecular weight chromatin remodelling factors which can facilitate transcription by binding to chromatinized DNA templates.

  • However, none of the above chromatin remodelling factors binds to specific DNA sequences.

  • Most of them are not toxic for endothelial cells, but impair the dynamic process of cell proliferation, migration and matrix remodelling.

  • One of great importance, urokinase (uPA) and its high affinity receptor, the GPI-anchored membrane CD87 (uPAR), is critical in tumour progression and its level of expression is correlated with poor prognosis of various cancers such as prostate [ 2 ] , breast [ 3 ] , colon [ 4 ] , ovarian [ 5 ] , gastric [ 6 ] , brain [ 7 ] , and lung cancer [ 8 ] . Urokinase (uPA) and its main product plasmin belong to the very early proteases [ 9 10 11 ] that activate the metallo-protease (MMP) cascade and therefore control cell motility, tissue remodelling and the activation of various angiogenic factors (VEGF, TGFβ).

  • In contrast, chromatin remodelling factors like SWI/SNF, ISW1, BRG1 facilitate transcription from chromatinised templates in the presence of ATP [ 18 ] . However, these factors do not bind to specific DNA sequences.


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