Example sentences for: relaxes

How can you use “relaxes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • If an elected official is doing a good job, how he relaxes during his free time is not a legitimate public concern.

  • DNA topoisomerase I (TOP1) is a ubiquitously expressed protein that relaxes DNA supercoils generated during many transactions of DNA including replication, transcription, repair, and chromatin condensation and remodeling.

  • Diagnostic plots of the four practice activity subscales suggested that an explanatory model might be best approached using logistic regression, which relaxes the assumption of normality.

  • She hits her slight speech impediment harder than usual and further relaxes her already shlumpy posture.

  • Prostaglandin E 2 is a major cyclooxygenase metabolite of arachidonic acid which exerts diverse effects on vascular smooth muscle tone and epithelial solute transport via G-protein coupled receptors [ 1 2 ] . At least four distinct G-protein coupled PGE 2 receptors have been cloned: the EP 1 , EP 2 , EP 3 , and EP 4 [ 1 ] . Pharmacological studies suggest PGE 2 relaxes vascular smooth muscle through two of these receptors, the EP 2 and EP 4 receptors, which couple to cyclic-AMP generation [ 3 ] . In contrast, PGE 2 constricts other vascular smooth muscle through EP 3 receptors which inhibit cAMP generation via G i or EP 1 receptors which increase Ca 2+mobilization [ 3 ] . Although both EP 2 and EP 4 receptors relax smooth muscle, EP 2 receptors are uniquely sensitive to the agonists butaprost and AH13205 [ 3 4 ] . Previous studies have shown that PGE 2 increases the cAMP concentration in many tissues including kidney, intestine and uterus, but the relative contribution of EP 2 versus EP 4 receptors to these effects is incompletely defined [ 5 6 ] . Recent studies in mice with targeted disruption of these receptors have suggested an important role for EP2 receptor in regulating systemic hemodynamics.


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