Words similar to relapse-free
Example sentences for: relapse-free
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This finding suggests that the expression of these proteins in breast cancer is regulated by soluble factors produced by the tumor cells [ 26 27 ] . High levels of expression of HGF and Met are associated with invasive breast cancer, and might be causally linked to early recurrences, metastatic disease and shortened survival of breast cancer patients [ 28 29 ] . High levels of HGF/SF detected within breast tumor extracts are correlated with larger tumor size and shorter relapse-free and overall survival compared with tumors with low HGF/SF concentration [ 30 ] .
Patients in the CM, LOH group had 5 year relapse-free survival, locoregional control and cause specific survival that were statistically indistinguishable from those in the CM, non LOH group (p > 0.2).
Patients in the RT, LOH group also fared worse than those in the combined modality (CM), LOH group, although the differences were not statistically significant in these smaller subgroups: 5 year relapse-free survival {23% (95% CI: 2% to 44%) vs. 54% (95% CI: 26% to 82%); p = 0.18}, locoregional control {34% (95% CI: 11% to 57%) vs. 61% (95% CI: 34% to 88%); p = 0.25} and cause specific survival {29% (95% CI: 5% to 53%) vs. 59% (95% CI: 30% to 88%); p = 0.12}.
The clinical trial from which the tumor specimens used in this study were derived showed improvements in relapse-free survival, locoregional control, and overall survival for those patients randomized to combined modality therapy [ 31 ] . This investigation established that patients whose tumors had M6P/IGF2R loss of heterozygosity and were treated with radiotherapy alone had a significantly worse prognosis than their counterparts with a non-mutated allele.
Patients in the radiotherapy (RT), loss of heterozygosity (LOH) group had significantly lower 5 year relapse-free survival {23% (95% CI: 2% to 44%) vs. 69% (95% CI: 46% to 92%); p = 0.02} (Figure 2), locoregional control {34% (95% CI: 11% to 57%) vs. 75% (95% CI: 54% to 98%); p = 0.03} (Figure 3) and cause specific survival {29% (95% CI: 5% to 53%) vs. 75% (95% CI: 54% to 96%); p = 0.02} (Figure 4) than those in the RT, non LOH group.
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