Example sentences for: rel

How can you use “rel” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The inhibitor studies correlating chemokine gene expression and NF-κB binding activity indicate that RSV, in contrast to TNFα, induces IL-8, MCP-1 and RANTES expression in A549 epithelial cells through a redox-sensitive NF-κB signaling pathway that appears to involve predominately Rel A. IL-8, MCP-1 and RANTES are known redox regulated genes and our results are consistent with the findings that oxidant tone can regulate chemokine gene expression in RSV infected airway epithelial cells [ 46 47 48 ] .

  • 4B) markedly induced Rel A, the transcriptionally active subunit of NF-κB.

  • Initially we detected TNFα and RSV induction of NF-κB by EMSA (KA Roebuck and LR Carpenter unpublished data) but because multiple gel shift complexes were induced it was not possible to distinguish the individual contributions of Rel A and p50 to the formation of these complexes.

  • NF-κB binds to the chemokine promoter as either homo- or heterodimers composed of Rel A (p65) and NF-κB1 (p50).

  • 4, Rel A and p50 subunits are differentially inhibited by NAC and DEX which have been shown to inhibit NF-κB by distinct mechanisms.


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