Words similar to rel

Example sentences for: rel

How can you use “rel” in a sentence? Here are some example sentences to help you improve your vocabulary:

Both NAC and DEX were unable to inhibit TNFα induction of either Rel A or p50.
TNFα rapidly and potently activates Rel A and p50 subunits of NF-κB through a kinase-mediated phosphorylation cascade involving a high molecular mass signaling complex called the IKK complex [ 56 ] . TNFα activation of the multiprotein IKK complex results in the serine phorsphorylation of I-κB and the subsequent activation of NF-κB [ 57 ] .
NAC is an antioxidant thiol that raises the intracellular pool of glutathione the major redox regulating mechanism in the A549 epithelial cell line [ 45 ] . Interestingly, it has been reported that NAC can have differential effects on NF-κB binding activity suggesting only a subset of NF-κB binding complexes are redox sensitive [ 58 ] . Moreover, it has been shown that NAC inhibits Rel A/p50 heterodimers but not p50 homodimers and can inhibit NF-κB binding to only certain variant κB elements which presumably interact with distinct redox sensitive NF-κB binding complexes [ 59 ] . These observations are consistent with our findings that indicate NAC predominantly inhibits Rel A homodimers since that was the major NF-κB subunit induced by RSV infection of A549 cells.
NF-κB binds to the chemokine promoter as either homo- or heterodimers composed of Rel A (p65) and NF-κB1 (p50).
4, Rel A and p50 subunits are differentially inhibited by NAC and DEX which have been shown to inhibit NF-κB by distinct mechanisms.