Example sentences for: rel

How can you use “rel” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 4B) markedly induced Rel A, the transcriptionally active subunit of NF-κB.

  • Our findings suggest that RSV induction of chemokine gene expression involves a redox-sensitive NF-κB signaling mechanism that differs from that mediated by TNFα and involving predominantly the Rel A subunit of NF-κB.

  • Toll and Tube are members of a signal transduction pathway that activates the Rel transcription factor Dorsal and is involved in developmental patterning and in the adult immune response.

  • 4, Rel A and p50 subunits of NF-κB are differentially expressed and induced in A549 epithelial cells.

  • NAC is an antioxidant thiol that raises the intracellular pool of glutathione the major redox regulating mechanism in the A549 epithelial cell line [ 45 ] . Interestingly, it has been reported that NAC can have differential effects on NF-κB binding activity suggesting only a subset of NF-κB binding complexes are redox sensitive [ 58 ] . Moreover, it has been shown that NAC inhibits Rel A/p50 heterodimers but not p50 homodimers and can inhibit NF-κB binding to only certain variant κB elements which presumably interact with distinct redox sensitive NF-κB binding complexes [ 59 ] . These observations are consistent with our findings that indicate NAC predominantly inhibits Rel A homodimers since that was the major NF-κB subunit induced by RSV infection of A549 cells.


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