Words similar to reinitiation
Example sentences for: reinitiation
How can you use “reinitiation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Forty-two eligible patients from the Jonathan Lax Immune Disorder Clinic in Philadelphia, Pennsylvania, were randomized via sealed envelopes in a 1:1 fashion to a first phase (phase I) of either (1) three successive TIs of 2, 4, and 6 wk, respectively, or (2) maintenance of ART for 40 wk before a final interruption of therapy in both arms (phase II) subject to therapy reinitiation criteria as described below.
It is of interest to note that despite the large amount of research activity on TIs in patients with suppressed chronic infection and the hundreds of monitored interruptions studied to date, only limited cases of development of clinical resistance (as evidenced by a lack of viral resuppression following therapy reinitiation) have emerged, in contrast to the multiple reports of detection of viral sequences off ART associated with resistance as shown in this study and others [11,19,29,30,39,40].
These HIV-1-specific CD4+ T cell responses also tended to rise with reinitiation of therapy, and some of them were very robust, with stimulation indices over 50 detected in several individuals (Figure 3E).
Following reinitiation of therapy after phase II, patients suppressed viral replication to less than 50 copies/ml by a median time of 10 (6–12) wk in both arms, excluding for two patients in the continuous therapy/single interruption arm who elected to stay off ART indefinitely and one patient from the repeated interruptions arm who reported nonadherence following regimen reinitiation yet reached 52 copies/ml before withdrawing from additional follow-up.
when measured between arms before the open-ended TI (see Figure 4), nor following resuppression after monitored TI reinitiation cycles in the repeated interruptions arm (see Figure 5).
Loading...