Words similar to refractory

Example sentences for: refractory

How can you use “refractory” in a sentence? Here are some example sentences to help you improve your vocabulary:

It is widely agreed, even though this is controversial too, that in patients with advanced cancer and other terminal diseases the provision of sedation leading to unconsciousness sometimes can be a necessary therapeutic procedure of last resort for symptom relief [ 1 ] . In the final stages of life, symptoms may remain refractory.
This finding is in confirmation with other studies, in which besides acute bleeding and gastrointestinal symptoms, distressing dyspnoea, delirium and agitated anxiety also where found to be the main reasons for sedation in end-of-life care [ 32 ] . The adequate treatment and care of patients of patients with otherwise refractory symptoms certainly is a great challenge in palliative care and improvement in this field is needed urgently.
Depletion of TBP and TAF II135 is not observed in F9 cells which are refractory to T-RA.
For both drugs in this study, tumors were considered refractory if they did not undergo sufficient shrinkage to qualify for partial response.
Sedation should be restricted as a reversible therapeutic option to otherwise refractory suffering by burdensome symptoms in the terminal and final phase, which may, but should not intentionally, hasten death.