Words similar to refractory
Example sentences for: refractory
How can you use “refractory” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is important to consider, however, that any hallmark sequence structures uniquely associated with the insertion of structural variants may be refractory to analysis after millions of years of evolution.
Ethically acceptable criteria and guidelines for decision making with regard to the nature of refractory and intolerable symptoms, patients' needs, aims of sedation and informed consent are needed [ 49 ] . Based on these, prospective clinical studies with systematic documentation of cases, transparency and critical communication with regard to indications, intentions, procedures, alternatives, results and adverse effects would help to locate the appropriate place of sedation in end-of-life care and diminish misuse or moral prejudices.
Patients were eligible for this protocol if their leukemia was: 1) refractory to previous induction chemotherapy, 2) in first or subsequent relapse after initial complete remission following induction chemotherapy, 3) secondary to transformation from an antecedent hematologic disorder, or 4) secondary to previous exposure to cytotoxic agents.
Sedation should be restricted as a reversible therapeutic option to otherwise refractory suffering by burdensome symptoms in the terminal and final phase, which may, but should not intentionally, hasten death.
The intention is the relief of otherwise intractable and refractory distress [ 18 ] . Target symptoms include persisting pain, delirium, dyspnoea, nausea and vomiting, massive haemorrhage, agitated anxiety and other forms of psychological distress.
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