Words similar to refractory

Example sentences for: refractory

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10B) showing that these cells are refractory to the differentiating effect of bt 2 cAMP.
Ethically acceptable criteria and guidelines for decision making with regard to the nature of refractory and intolerable symptoms, patients' needs, aims of sedation and informed consent are needed [ 49 ] . Based on these, prospective clinical studies with systematic documentation of cases, transparency and critical communication with regard to indications, intentions, procedures, alternatives, results and adverse effects would help to locate the appropriate place of sedation in end-of-life care and diminish misuse or moral prejudices.
Prokinetic agents (eg, metoclopramide) added to the regimen may assist the occasional patient whose constipation is refractory.
Despite expression of levels of hCARΔcyt comparable to that of double-negative and single-positive thymocytes, double-positive thymocytes were relatively refractory to reporter expression following transduction with either the Ad5.UbP.GFP or Ad5.CMV5.GFP vector.
This finding is in confirmation with other studies, in which besides acute bleeding and gastrointestinal symptoms, distressing dyspnoea, delirium and agitated anxiety also where found to be the main reasons for sedation in end-of-life care [ 32 ] . The adequate treatment and care of patients of patients with otherwise refractory symptoms certainly is a great challenge in palliative care and improvement in this field is needed urgently.