Words similar to rect
Example sentences for: rect
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The clustering of functionally related genes in prokaryotic genomes into co-transcribed and co-regulated units, operons, often allows functional assignments through the principle of 'guilt by association' [ 30 31 32 ] . Generally, genes whose products physically interact to form a complex or are involved in successive steps in a biochemical pathway form operons that are conserved over large evolutionary distances [ 30 ] . On previous occasions, we have used gene neighborhoods or operons to predict novel DNA repair complexes and their components [ 33 ] . Accordingly, a similar approach was applied to the three families of SSAPs (RecT/Redβ, ERF, Rad52), to shed light on their functional links.
This suggests that, at some stage in their evolution, the Bacillus recT gene protein has recombined with the gene coding for SSB, which might even have resulted in a functional replacement of an SSB with an SSAP.
RecT and Redβ are evolutionarily related and define a widespread family of DNA recombination proteins
Previously, the RecT proteins have been known from very few bacteria and Redβ has only been detected in λ and closely related phages.
We unify the Redβ and RecT proteins and their homologs, which have not been reported as being related at the sequence level, into a single superfamily, supporting the notion that these proteins share a similar mechanism of action.