Example sentences for: receptor-ligand

How can you use “receptor-ligand” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • HGF/SF induces mitogenic and morphogenic changes, including rapid membrane ruffling, formation of microspikes, and increased cellular motility [ 12 13 ] . The diverse biological effects of HGF/SF are all mediated by Met, which is preferentially expressed on epithelial cells [ 14 ] . In vivo this receptor-ligand pair is essential for normal embryonic development [ 15 16 ] . Whereas Met signaling clearly has a role in normal cellular processes, this signaling pathway has also been implicated in tumor development and progression.

  • Several techniques have been developed to predict the binding energies of HIV-1 protease-inhibitor complexes [ 16 17 18 19 20 21 ] . Head RD et al ., 1996 [ 16 ] used an approach that calculates physicochemical properties of the ligands and the receptor-ligand complexes to estimate the free energy of binding.

  • The EGF domain, which often occurs as multiple tandem repeats, is widely distributed among extracellular proteins involved in adhesion, receptor-ligand interactions, extracellular matrix structure, determination of cell fate, and blood coagulation [ 27 ] . Cell adhesion usually activates PI 3-kinase activity.

  • It is notable that one of the closest pairs formed consists of a receptor-ligand pair: VEGF and NRP2 (Figure 3).

  • The yeast two-hybrid system strategy has been used to examine both intracellular and receptor-ligand protein-protein interactions.


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