Example sentences for: re-uptake

How can you use “re-uptake” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Clomipramine is a non-selective re-uptake inhibitor of serotonin, and to some extent norepinephrine [ 21 ] and fluoxetine is a selective serotonin re-uptake inhibitor [ 22 ] . Both of these drugs have proven to be effective in different animals models of OCD [ 23 ] . As an additional control, hamsters were also treated with desipramine, a noradrenergic re-uptake inhibitor [ 24 ] that has been found ineffective in inhibiting OCD in preclinical [ 25 ] and clinical studies [ 26 27 ] .

  • Selective serotonin re-uptake inhibitors are recognized as an effective biological treatment for OCD [ 20 ] . In a double blind, placebo control study, treating over 500 patients with OCD, clomipramine was found to be superior to placebo [ 30 ] . Differences between clomipramine and placebo were noted as early as one week after the start of treatment, with significant clinical improvement occurring after six weeks of treatment.

  • The present data show that AVP-induced flank marking is selectively inhibited by chronic treatment with serotonin re-uptake inhibitors such as fluoxetine or clomipramine, instead of noradrenergic re-uptake inhibitors such as desipramine.

  • Fluoxetine also results in a significant reduction in OCD severity that takes several weeks to realize [ 31 32 ] . This therapeutic delay has been related to a down-regulation of serotonin autoreceptors with chronic exposure to elevated serotonin [ 33 34 ] . Together, these data have been used to link OCD with a dysfunction in serotonin neurotransmission [ 35 ] . Of course, it is unclear whether prolonged treatment with these re-uptake inhibitors is restricted to serotonin alone or impact on the activity of other neurotransmitter systems.

  • As noted earlier, fluoxetine is a selective serotonin re-uptake inhibitor while clomipramine is a non-selective re-uptake inhibitor of serotonin, and to some extent norepinephrine.


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