Words similar to rbf

Example sentences for: rbf

How can you use “rbf” in a sentence? Here are some example sentences to help you improve your vocabulary:

However, in our experimental situation, we did not observe any modification of the mCul1 overexpression phenotype by mutations in either the RBF or DP gene, two known partners of E2F.
The E2F/RBF complex has to be disrupted for E2F to drive cells into S phase and E2F degradation occurs after the G1/S phase transition which only happens after E2F has been released from its association with RBF.
This result suggests that these factors are not limiting factors in this situation or that E2F acts independently of RBF and DP.
The latter hypothesis is the most likely explanation for the lack of an RBF interaction for the following reason.
For example, a slimb allele shows defects in centrosome duplication control [ 34 ] , and slimb null cells undergo apoptosis [ 35 ] . Both effects could be explained by a failure to inactivate E2F, as E2F promotes centrosome duplication in mammalian cells [ 36 ] and E2F can induce apoptosis [ 12 ] [ 13 ] . A link between Slimb function and the RB/E2F pathway of cell proliferation control is also suggested by the genetic interaction between the C. elegans slimb ortholog lin-23 and the RBF ortholog lin-35 in which lin-35 function limits the severity of the loss of lin-23 [ 37 ] . Since RBF is an important modifier of E2F activity, perhaps this interaction is a reflection of the action of both Lin-23 and Lin-35 on E2F.