Example sentences for: rab

How can you use “rab” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Such structures were never observed in cells expressing mycRab24wt or any other over-expressed Rab GTPase.

  • Rab24 is known to be expressed endogenously in many cell types, including the cell lines used in these studies [ 24 25 ] , and we have estimated that both mycRab24wt and D123I are transiently expressed 5-10 fold over the level of endogenous Rab24 (data not shown).

  • Although Rab24 has been proposed as a possible regulator of autophagic processes [ 24 43 ] , the accumulation of punctate bodies in cells expressing Rab24(D123I) was not prevented by 3-methyadenine, a known inhibitor of autophagosome formation [ 44 ] . Most importantly, electron microscopy with immunogold labeling of mycRab24(D123I) in ultra-thin sections confirmed the initial impression that the inclusions are in fact localized within the nucleus.

  • Western blot analyses of cytosol and particulate fractions obtained from the transfected 293 cells indicated that mycRab24(wt) was present in both fractions, consistent with previous results with Rab24 and other wild-type Rab GTPases [ 25 39 ] . In contrast, mycRab24(D123I) was found exclusively in the particulate fraction (Fig.

  • To detect the expressed myc-tagged Rab proteins, cells were incubated for 60 min with either the 9E10 mouse monoclonal antibody against the myc epitope or a rabbit polyclonal antibody against the same epitope (Upstate Biotechnology, Lake Placid, NY).


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