Example sentences for: rab

How can you use “rab” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These unique properties of Rab24 suggest that it may not function according to the accepted cyclical model.

  • We noted that the inclusions caused by expression of Rab24(D123I) were similar morphologically to those described in some of the poly-Gln disorders and hypothesized that they might arise via a similar pathway.

  • Although Rab24 has been proposed as a possible regulator of autophagic processes [ 24 43 ] , the accumulation of punctate bodies in cells expressing Rab24(D123I) was not prevented by 3-methyadenine, a known inhibitor of autophagosome formation [ 44 ] . Most importantly, electron microscopy with immunogold labeling of mycRab24(D123I) in ultra-thin sections confirmed the initial impression that the inclusions are in fact localized within the nucleus.

  • Rab24 guanine nucleotide state

  • Here we have shown that single amino acid substitutions ( e.g. , D123I and T120A) in one of the conserved guanine nucleotide binding domains of Rab24 can cause the protein to accumulate in a massive array of nuclear inclusions in mammalian cells.


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