Words similar to putative
Example sentences for: putative
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Mutagenesis studies have identified the interaction of amino acids W89 and R91 in the binding of 5-HT 3 R ligands [ 24 23 ] . Studies conducted in our laboratory have identified three additional putative binding site residues (Y140, Y142, and Y152) [ 25 ] . W89 and R91 are present in a conserved region of LGIC receptors often referred to as loop D [ 24 26 ] . Similarly, Y140, Y142 and Y152 are located in the region homologus to E loop region of nicotinic AchR.
Ipl in mice, and which encodes a putative decoy receptor in the TNF receptor family.
Putative exons on the 12-kb h174.
Although the putative functions in Table 1are not generally associated with virulence, many genes, under the right circumstances, can facilitate infection or contribute to pathogenicity.
The ability of a MIDAS protein to bind its protein ligand is tightly linked with the presence of intact MIDAS motifs: mutations to the metal-coordinating residues in these motifs, weaken or eliminate ligand binding [ 35 36 ] . An additional set of MIDAS-like proteins, that includes the integrin β-chain [ 37 38 ] and the von Willebrand Factor A domain [ 27 ] , lacks one of the three motifs and appears to bind ligands in a somewhat different manner [ 27 39 40 ] . In midasin, the presence of all three MIDAS motifs in the M-domain, with the putative metal ion-binding residues in the motifs invariant in the available organisms, indicates that midasin belongs to the family of MIDAS-containing proteins.