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Example sentences for: pufferfish

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Whereas the genome of Fugu rubripes is one order of magnitude shorter than the length of the human genome, the total number of genes is estimated to be approximately the same [ 8 9 ] . Because of the low homology of amino- and carboxyl-terminal sequences, we were not able to determine the complete coding sequences of the eight pufferfish TMC proteins unequivocally; nevertheless, we obtained sufficient sequence information of the central parts of the proteins bearing the transmembrane domains to classify the eight pufferfish TMCs into the three subfamilies.
This is intriguing considering that both mosquito and fly species belong to the same taxonomic order (Diptera), and diverged approximately 250 million years ago, as compared to the 450 million years separating pufferfish and humans [ 45 ] . It has been noted that only half the genes in the Drosophila and Anopheles genomes can be interpreted as homologues [ 46 ] . We have identified a 250 amino acid protein (CG12104-PA) in the Drosophila database, which contains a partial HMG-box motif with weak similarity to the TOX family.
We identified eight TMC loci in the Japanese pufferfish (Torafugu, Fugu rubripes , Fr) genomic database http://fugu.hgmp.mrc.ac.uk/.
The final clone isolated in our search encodes a 433 amino acid protein whose sequence was highly conserved from human to pufferfish.
A region of high similarity was found in the pufferfish gene in a location expected for exon 1b.