Words similar to pudendal
Example sentences for: pudendal
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Alpha1 adrenergic antagonists have been shown to inhibit pudendal reflexes in anesthetized cats [ 24 25 26 ] . However, a systemic dose of prazosin (alpha1 antagonist) did not inhibit the EUS EMG activity during high frequency oscillations in the rat [ 27 ] . Thus, although alpha1 antagonism has been shown to modulate pudendal reflexes in the cat, their role in modulating the activity of the EUS during micturition in the rat appears unclear.
In cats, serotonin antagonists caused a decrease in bladder capacity [ 43 ] however in anesthetized rats, serotonin antagonism did not have an effect on micturition [ 44 ] . Recently, a selective 5-HT1A receptor antagonist (WAY-100635) was reported to inhibit bladder contractions in rats [ 45 ] yet another report only observed an increase in the pressure threshold [ 46 ] . Olanzapine and risperidone have only low to modest affinity for the 5-HT1A receptor, and higher affinities for the 5-HT2A and 5-HT2C receptors [ 11 12 ] . Serotonin 5-HT2 and 5-HT3 receptors facilitate pudendal reflexes in the cat [ 47 48 ] , therefore it is possible that antagonism of these receptors may block the EUS in the anesthetized rat.