Words similar to pudendal

Example sentences for: pudendal

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In cats, serotonin antagonists caused a decrease in bladder capacity [ 43 ] however in anesthetized rats, serotonin antagonism did not have an effect on micturition [ 44 ] . Recently, a selective 5-HT1A receptor antagonist (WAY-100635) was reported to inhibit bladder contractions in rats [ 45 ] yet another report only observed an increase in the pressure threshold [ 46 ] . Olanzapine and risperidone have only low to modest affinity for the 5-HT1A receptor, and higher affinities for the 5-HT2A and 5-HT2C receptors [ 11 12 ] . Serotonin 5-HT2 and 5-HT3 receptors facilitate pudendal reflexes in the cat [ 47 48 ] , therefore it is possible that antagonism of these receptors may block the EUS in the anesthetized rat.
Alpha1 adrenergic antagonists have been shown to inhibit pudendal reflexes in anesthetized cats [ 24 25 26 ] . However, a systemic dose of prazosin (alpha1 antagonist) did not inhibit the EUS EMG activity during high frequency oscillations in the rat [ 27 ] . Thus, although alpha1 antagonism has been shown to modulate pudendal reflexes in the cat, their role in modulating the activity of the EUS during micturition in the rat appears unclear.