Words similar to pseudopods
Example sentences for: pseudopods
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The phenotype induced by ADP-ribosylation of Rho in T lymphocytes appeared different than that induced in fibroblast models, where microinjection of C3 results in fibroblast retraction of pseudopodia, with the cell body rounding up eventually to become non-adherent [ 17 ] . Video time-lapse microscopy demonstrated the elongation of aberrant pseudopods in HPB-ALL cells plated on the β1 substrate VCAM-1, rather than an altered retraction of already formed pseudopods.
The cells expressing GFP-MHCK-B appeared to have smooth cell edges because the fluorescence did not label the dynamic pseudopods at the leading edge of the cell, compared with that in GFP-MHCK-A cells.
The notable exception was that clusters of RhoA appeared less diffuse in the altered pseudopods of C3 treated cells (figure 6).
Thus, functional Rho is required for the proper extension and retraction of pseudopods in T lymphocytes on β1 integrin substrates.
The phenotype induced by C3 mediated ribosylation of Rho in HPB-ALL could result from either aberrant retraction of recently formed pseudopods, or altered pseudopodial extension.