Words similar to pseudo-counts

Example sentences for: pseudo-counts

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Calculation of the pseudo-counts was based on the degree of diversity and statistical substitution probabilities for the specific residues occurring in each of the alignment columns.
Finally, the log-odds of occurrence of a specific residue is obtained from the logarithm of the sum of real and pseudo-counts divided by the background frequency that would occur in a random sequence by chance.
To these real residue counts, pseudo-counts were added to better approximate the full set of related sequences in nature (of which only an incomplete, non-random sample is known).
The recommended value of 5.0 times the residue diversity was used for the total number of pseudo-counts, and the amino acid substitution probabilities were taken from the BLOSUM 62 matrix [ 22 ] . A substitution matrix based on transmembrane helices [ 23 ] was also used in some cases, however, the results were not altered substantially.