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Example sentences for: protrusions
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Both precursor and effector cells of this activity were typically NK cells [ 11 ] . Direct evidence that NK cells are the mediators of LAK activity came from Immunotransmission Electron microscopic studies using colloidal gold labeled antibodies in which CD16 positive cells were shown to extend their protrusions deep into the target cells and it was found that the cytoplasmic granules and vacuoles of CD16 positive LAK cells were concentrated in the area of the binding site [ 12 ] . With the advent of flowcytometry and immunophenotyping we thought we could approach this dilemma in a different but simple and straightforward manner.
It was excluded from the polar protrusions, as seen by the smooth contour of the poles (Fig.
Previously, Steimle and colleagues [ 23 ] reported that in interphase cells, during chemotaxis, random migration, and endocytic/phagocytic events, MHCK-A is recruited preferentially to anterior F-actin rich protrusions.
Moving bacteria that reach the cell plasma membrane form membrane-bound protrusions that are engulfed by neighboring cells, allowing the infection to spread without the bacteria ever leaving the cytoplasmic environment.
This model is consistent with the recent report that MHCK-A displays enrichment into anterior F-actin-rich protrusions of polarized cells during chemotaxis, and into phagocytic and macropinocytotic extensions [ 23 ] . The polar localization of MHCK-A would be consistent with the long-standing "polar relaxation" model for cytoskeletal reorganization during cytokinesis [ 33 ] . MHCK-A may represent a factor that contributes to polar relaxation in this system via polar disassembly of myosin II filaments.
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