Words similar to protegrin
Example sentences for: protegrin
How can you use “protegrin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our studies demonstrate a correlation between protegrin sensitivity/resistance and protegrin binding in P. aeruginosa and B. cepacia , and support a hypothesis that the relative resistance of B. cepacia to protegrin is due principally to a reduced number of protegrin binding sites on the lipid A moiety of its LPS.
4indicate that at saturation (20 μM), lipid A from B. cepacia bound almost exactly one-half as many protegrin molecules as lipid A from P. aeruginosa . How might this be rationalized?
In model systems, the ability of protegrins to permeabilize membranes shows pronounced "concentration-gating", an indication that it is influenced by the density of bound protegrin molecules per unit area of membrane [ 47 ] . As prior quantitative studies of peptide binding are few in number, some readers may be surprised to note that Fig.
1shows many millions of protegrin molecules are bound to an average bacterial cell, even at concentrations around the minimal active concentration.
This protegrin variant differed from PG-1 in two ways: Phe7 replaced Tyr7 in the protegrin domain, and an N-terminal glycine-rich hexapeptide extension (GGGYGG) with a single tyrosine residue was present.