Example sentences for: protegrin

How can you use “protegrin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our studies demonstrate a correlation between protegrin sensitivity/resistance and protegrin binding in P. aeruginosa and B. cepacia , and support a hypothesis that the relative resistance of B. cepacia to protegrin is due principally to a reduced number of protegrin binding sites on the lipid A moiety of its LPS.

  • 4indicate that at saturation (20 μM), lipid A from B. cepacia bound almost exactly one-half as many protegrin molecules as lipid A from P. aeruginosa . How might this be rationalized?

  • In model systems, the ability of protegrins to permeabilize membranes shows pronounced "concentration-gating", an indication that it is influenced by the density of bound protegrin molecules per unit area of membrane [ 47 ] . As prior quantitative studies of peptide binding are few in number, some readers may be surprised to note that Fig.

  • 1shows many millions of protegrin molecules are bound to an average bacterial cell, even at concentrations around the minimal active concentration.

  • This protegrin variant differed from PG-1 in two ways: Phe7 replaced Tyr7 in the protegrin domain, and an N-terminal glycine-rich hexapeptide extension (GGGYGG) with a single tyrosine residue was present.


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