Example sentences for: propranolol

How can you use “propranolol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Control cells were treated with 10 μM propranolol only.

  • For induction of the Rfz-2/β 2 AR chimeric receptor, chimeric receptor expressing C57mg cells or wt C57mg cells were treated with 10 μM propranolol overnight and then with 10 μM isoproterenol for 8 hours.

  • Both in animal and human studies of heart failure, β-adrenergicblockade intervention appears to have beneficial effects on cardiacmyocyte function [ 1 23 24 ] . Of particularimportance, studies using carvedilol have shown remarkable improvementsin cardiac performance [ 12 13 15 16 ] andreduction in mortality in humans [ 17 ] .We have previously shown that propranolol, a nonselective β-blocker,is cardioprotective and prevents the development of heart failurein turkeys when given concurrently with furazolidone [ 21 ] . Similarly, carteolol, a nonselective β-blocker,resulted in improvement in ejection fraction, reduction in ventricularvolumes, an increase in developed pressure as well as an increasein rate of survival in our turkey model [ 18 ] . Improvementin cardiac function was associated with cellular remodeling of cardiacmyocytes.

  • This model is similar to that used to describe human propranolol pharmacokinetics [ 26 ] . The model input goes directly into the venous compartment, bypassing the liver, and the solute clearance is produced entirely by renal secretion so that the input function ("absorption" rate) is equal to the systemic availability.

  • Figure 1shows the result of applying this technique to experimental data for three different solutes in humans: ethanol [ 24 ] (with or without a meal), standard propranolol [ 26 ] and a long acting form of propranolol [ 26 ] . The squares in these figures describe the time course of the total absorption as determined by PKQuest.


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