Words similar to propranolol
Example sentences for: propranolol
How can you use “propranolol” in a sentence? Here are some example sentences to help you improve your vocabulary:
Both in animal and human studies of heart failure, β-adrenergicblockade intervention appears to have beneficial effects on cardiacmyocyte function [ 1 23 24 ] . Of particularimportance, studies using carvedilol have shown remarkable improvementsin cardiac performance [ 12 13 15 16 ] andreduction in mortality in humans [ 17 ] .We have previously shown that propranolol, a nonselective β-blocker,is cardioprotective and prevents the development of heart failurein turkeys when given concurrently with furazolidone [ 21 ] . Similarly, carteolol, a nonselective β-blocker,resulted in improvement in ejection fraction, reduction in ventricularvolumes, an increase in developed pressure as well as an increasein rate of survival in our turkey model [ 18 ] . Improvementin cardiac function was associated with cellular remodeling of cardiacmyocytes.
Figure 1shows the result of applying this technique to experimental data for three different solutes in humans: ethanol [ 24 ] (with or without a meal), standard propranolol [ 26 ] and a long acting form of propranolol [ 26 ] . The squares in these figures describe the time course of the total absorption as determined by PKQuest.
For induction of the Rfz-2/β 2 AR chimeric receptor, chimeric receptor expressing C57mg cells or wt C57mg cells were treated with 10 μM propranolol overnight and then with 10 μM isoproterenol for 8 hours.
The results will be presented for the two different PBPK models: a) the solute distributes in all the tissue water with no tissue binding (referred to as "simple" model); and b) there is tissue binding of the solute, similar to what is observed for propranolol (referred to as "binding" model) (see Methods section for a detailed description).
This result is consistent with the fact that a 2-exponential function is used in most of the recent experimental applications of deconvolution [ 18 33 34 ] . For the more "complicated" pharmacokinetic PBPK model where there is extensive tissue binding (similar to that for propranolol), a 2-exponential function fit is no longer adequate (fig.
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