Example sentences for: proinflammatory

How can you use “proinflammatory” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus the advent of the CD8 +CD28 -cell in aging, with its potential for proinflammatory cytokines, could have profound effects not only on autoimmune diseases, but on Alzheimer's disease as well since cytokines may contribute to the neuropathology [ 72 ] .

  • IL-10 is a potent monocyte/macrophage regulatory cytokine that inhibits expression of proinflammatory mediators [ 1 2 ] . Monocytes/macrophages, B cells, murine Th2 cells, and some CD8 +cells produce IL-10 [ 3 4 ] . Macrophages rapidly produce proinflammatory cytokines such as tumor necrosis factor alpha (TNF-α), IL-1 and IL-12 after activation with lipopolysaccharide or IFN-γ, while production of IL-10 is delayed.

  • The proinflammatory cytokine TNF has been shown to play a role in the pathogenesis of RA [ 9, 10].

  • IL-4 is able to inhibit IL-2 and IFN-γ production by Th1 cells, resulting in suppression of macrophage activation and the production of the proinflammatory cytokines IL-1, IL-6, IL-8, and TNF-α by monocytes and macrophages [ 5, 6, 7, 8, 9].

  • Leptin's proinflammatory role suggests that it may link energy homeostasis to the immune system [4,5].Ghrelin is a peptide hormone that stimulates appetite, fat production, and body growth—leading to increased food intake and body weight.


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