Example sentences for: programmed

How can you use “programmed” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Ongoing in vitro studies aim to evaluate the stereochemistry of phosphorothioyl binding to Fhit while in vivo studies test the effects of these compounds on programmed cell death.

  • The breakthrough came when test designers (or "psychometricians," as they like to call themselves) programmed computers to select questions based on your previous answers, just as in "." When you get a question right, the computer asks a harder one, and an easier one when you get one wrong.

  • Early in Austin Powers: The Spy Who Shagged Me , the stumpy, snaggletoothed British secret agent (Mike Myers) survives an assassination attempt by his new bride, Vanessa (Elizabeth Hurley), who turns out to have been a "fembot" programmed by his nemesis, Dr. Evil (also Myers), to blow up the couple's honeymoon suite after 15 rounds of zealous humping.

  • The available research regarding cognitive function and phytoestrogens suggests that large amounts of phytoestrogens, consumed as tofu, have an adverse influence on cognitive ability in men, where decreased brain weight, increased ventricular size and dementia have been reported [ 44 ] . In ovariectomized female rats, on the other hand, phytoestrogen treatments resulted in a dose-dependent improvement of VSM [ 45 ] . This improvement in cognitive ability in phytoestrogen treated females may be due in part to the increased presence of choline acetyltransferase messenger RNA in the frontal cortex, which has been shown to be associated with protection and enhancement of cognitive function [ 45 ] . Furthermore, we have shown that phytoestrogens significantly affect the brain calcium-binding protein calbindin (CALB), which acts as a buffer by binding intracellular calcium and plays an important role in mediating cell proliferation, programmed cell death (apoptosis), and neurotoxicity [ 48 49 50 51 52 ] . This neuroprotective mechanism via CALB appears to be important in neurological disorders such as Parkinson's disease and Huntington's disease [ 48 49 50 51 52 ] . Additionally, Cyclooxygenase-2 (COX-2) seems to play an important role in mediating functional neuronal maturation and responses to certain stimuli in the brain [ 53 54 55 ] . The expression of COX-2 is associated with key pathophysiologic events in Alzheimer's disease: deposition of beta-amyloid protein in neuritic plaques within the hippocampus and cortex [ 53 54 55 ] . Of particular importance to this study is the fact that COX-2 has been shown to be influenced by steroidal hormones [ 53 54 55 ] . Therefore, the expression of COX-2 in the frontal cortex may also be hormonally regulated and relevant to cognitive decline.

  • It is possible that intestinal cells are programmed for a more general response, and that controlling the severity of the response is the critical level of regulation.


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