Words similar to pro-inflammatory
Example sentences for: pro-inflammatory
How can you use “pro-inflammatory” in a sentence? Here are some example sentences to help you improve your vocabulary:
Furthermore, CDDO decreased the expression of the pro-inflammatory mediator Bcl-3, suggesting one possible mechanism of action.
This is the first demonstration that treatment of wounds with a pro-inflammatory and angiogenic chemokine accelerates development of the granulation tissue during healing by stimulating the precocious deposition of ECM molecules that are critical for proper healing.
Making incisions into the rabbits may have caused an increase in pro-inflammatory cytokines.
Triterpenoids are a novel family of steroid-like compounds with weak anti-inflammatory properties [ 18 ] . Synthetic triterpenoids have been produced with the aim of achieving increased potency [ 19 20 ] . 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO) is a synthetic triterpenoid that has been shown to inhibit expression of the inflammatory genes inducible nitric oxide synthase and cyclo-oxygenase-2 [ 20 21 22 ] . In a recent report, MMP-1 and MMP-13 expression were induced with IL-1, a known pro-inflammatory mediator in vivo in joint tissues [ 23 ] . It was shown that CDDO could inhibit the IL-1-induced expression of these pro-inflammatory MMPs.
Monocyte/macrophage infiltration has a key role in the pathogenesis of chronic arthritis [ 8 ] . The release of pro-inflammatory cytokines, chemokines, growth factors, and enzymes by the synovial lining macrophages is important for the onset, propagation, and flare of arthritic inflammation [ 9 ] . The finding that the number of synovial tissue macrophages is correlated with joint destruction in rheumatoid arthritis is evidence of their importance [ 9 10 ] . Monocytes and macrophages are believed to have a similar role in other chronic inflammatory joint diseases, such as gout [ 11 ] and psoriatic arthropathy [ 12 ] . Therefore in this study we assessed the effects of mactinin on monocyte chemotaxis in vitro . We have also tested synovial fluid from patients with various types of arthritis, including rheumatoid arthritis, psoriatic arthritis, reactive arthritis, gout, and ankylosing spondylitis, for the presence of the monocyte/macrophage maturation-promoting fragment, mactinin.
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