Example sentences for: pro-inflammatory

How can you use “pro-inflammatory” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In endotoxic shock, bacterial endotoxin enters the systemic circulation and triggers the release of pro-inflammatory mediators.

  • MAdCAM-1 is a 60 kDa endothelial cell surface molecule that is strongly expressed by mucosal endothelial cells, particularly following exposure of these cells to pro-inflammatory cytokines such as TNF-α.

  • Beyond this, it may be assumed, given the powerful pro-inflammatory activity of the receptor, that germline or somatic mutations of TLR4 could in some instances cause constitutive signal transduction (as observed with the Drosophila Toll locus [ 31]).

  • We also studied the effect of SRL on pro-inflammatory cytokine TNF-α in lymphocytes from these patients (Figure 4).

  • Although the etiologies and pathologies of RA and OA differ, it is clear that in both of these diseases pro-inflammatory cytokines are present, resulting in an inflammatory state as well as cartilage degradation [ 14 ] . As further evidence for the role of pro-inflammatory cytokines in RA, anti-tumor necrosis factor-α (anti-TNF-α) and anti-interleukin 1 (anti-IL-1) therapies can reduce inflammation and retard the progression of disease as assessed radiographically [ 15 16 ] . However, side-effects with these approaches, such as the development of lymphomas in patients using anti-TNF-α therapies, demonstrate that alternative therapies are needed [ 17 ] .


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