Words similar to pro-inflammatory
Example sentences for: pro-inflammatory
How can you use “pro-inflammatory” in a sentence? Here are some example sentences to help you improve your vocabulary:
Beyond this, it may be assumed, given the powerful pro-inflammatory activity of the receptor, that germline or somatic mutations of TLR4 could in some instances cause constitutive signal transduction (as observed with the Drosophila Toll locus [ 31]).
Monocyte/macrophage infiltration has a key role in the pathogenesis of chronic arthritis [ 8 ] . The release of pro-inflammatory cytokines, chemokines, growth factors, and enzymes by the synovial lining macrophages is important for the onset, propagation, and flare of arthritic inflammation [ 9 ] . The finding that the number of synovial tissue macrophages is correlated with joint destruction in rheumatoid arthritis is evidence of their importance [ 9 10 ] . Monocytes and macrophages are believed to have a similar role in other chronic inflammatory joint diseases, such as gout [ 11 ] and psoriatic arthropathy [ 12 ] . Therefore in this study we assessed the effects of mactinin on monocyte chemotaxis in vitro . We have also tested synovial fluid from patients with various types of arthritis, including rheumatoid arthritis, psoriatic arthritis, reactive arthritis, gout, and ankylosing spondylitis, for the presence of the monocyte/macrophage maturation-promoting fragment, mactinin.
Although the etiologies and pathologies of RA and OA differ, it is clear that in both of these diseases pro-inflammatory cytokines are present, resulting in an inflammatory state as well as cartilage degradation [ 14 ] . As further evidence for the role of pro-inflammatory cytokines in RA, anti-tumor necrosis factor-α (anti-TNF-α) and anti-interleukin 1 (anti-IL-1) therapies can reduce inflammation and retard the progression of disease as assessed radiographically [ 15 16 ] . However, side-effects with these approaches, such as the development of lymphomas in patients using anti-TNF-α therapies, demonstrate that alternative therapies are needed [ 17 ] .
Making incisions into the rabbits may have caused an increase in pro-inflammatory cytokines.
MIF is a pro-inflammatory cytokine that may play a crucial role in initiating or maintaining several inflammatory conditions [ 1 ] . In experimental models, treatment with antibodies to MIF, reversed or prevented colitis and gastric ulcer formation [ 23 24 ] . MIF is upregulated in neurons in the brain and released into the CSF following intracisternal LPS or spinal cord injury [ 7 21 ] . In addition, MIF is upregulated in the brain after reperfusion subsequent to ischemia [ 25 ] . Therefore, MIF is likely involved in the brain's response infectious agents or trauma.
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