Example sentences for: prion

How can you use “prion” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, recent experiments demonstrated that [RNQ + ] prion dramatically stimulated aggregation of fragments of recombinant human huntingtin or ataxin-3 with an expanded polyQ domain cloned in yeast (Osherovich and Weissman 2001; Meriin et al.

  • Strict conformation requirements for aggregate formation can also explain interspecies transmission barriers, where prion domains of Sup35 derived from other yeast species cannot cause formation of [PSI + ] prion in Saccharomyces cerevisiae, in spite of a high degree of homology.

  • One member of the Nobel Committee says his colleagues were aware of unanswered questions in the prion hypothesis but awarded Prusiner the prize in recognition of the wealth of information he has unearthed on mad-cow-like diseases.

  • Two years later, when he presented the same mice work at another conference, the news pages of Science and Nature wrote it up as if it cinched the prion hypothesis.

  • They noted that both prion proteins contain an oligopeptide repeat QGGYQ in close proximity to Q/N-rich sequences and examined the functional significance of the repeats for aggregation and maintenance of the prions.


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