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Example sentences for: presumptive
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Excess neurons also developed in mouse embryos homozygous for targeted mutation of HES1 , a presumptive downstream effector of Notch signaling [ 36].
The dihydropyridine receptor (DHPR) of skeletal muscle consists of α 1S , α 2 , β 1a and γ 1 subunits [ 1 ] . The α 1 subunit is a large four-repeat transmembrane protein of ~220 KDa that contains the basic functional elements of the L-type Ca 2+channel, including the Ca 2+selective pore and S4 "voltage-sensing" transmembrane segments in each of the four internal repeats [ 2 ] . β subunits are ~65 kDa cytosolic proteins essential for membrane trafficking, modulation of channel kinetics, and for excitation-contraction (EC) coupling [ 3 4 ] . The α 2 subunit is a highly glycosylated ~175 kDa protein formed by two disulfide-linked peptides [ 5 ] , whereas the γ 1 subunit is a ~32 kDa skeletal muscle-specific protein of four presumptive transmembrane domains with almost unknown function [ 6 7 ] .
With this strategy were able to generate presumptive "framework" contigs for the in databases less abundantly represented TMC genes.
Finally, dlA dx2 mutant embryos had greatly reduced numbers of presumptive radial glia cells, labeled by antibody zrf-1 (Figure 5M,N).
2 position in government, JQA was the presumptive front-runner in the 1824 presidential race, though it was Andrew Jackson who won a plurality (yet not the necessary majority) of electoral votes.