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Example sentences for: presumed
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The presence of these outliers affects multiple alignment and phylogenetic models and in ET analysis can misrepresent the functional variability at the presumed PIC level.
It is presumed that most of them will form RNA duplexes with complementary sequences in mRNA, but direct regulatory relationships are known for only a handful of miRNAs.
The normal intima of the synovium is one to two cells thick and consists mainly of macrophage-like and fibroblast-like cells [ 3 ] . In inflammation, macrophages make a large contribution to intimal thickening, where these cells increase in number and proportion [ 3 ] . Evidence indicates that intimal macrophages arrive via the circulation as monocytes [ 4 ] , and it is proposed that increased numbers of intimal macrophages in RA are largely attributed to enhanced monocyte recruitment from blood vessels in the synovium [ 1 5 ] . Neutrophils are also recruited in RA and can be found in abundance in synovial fluid, yet they occur in relatively low numbers in the synovium [ 5 ] . In synovial fluid their number can reach 10 6per joint, particularly during an active phase of the disease [ 6 ] . Neutrophils occur at the pannus-cartilage junction [ 7 ] and it is presumed that these cells reach the joint cavity by migrating from the blood vessels in the synovium, following a chemotactic gradient.
Presumed Message: Something about reading pornography to kids?
The presumed ligand for Tlr4 is LPS itself, presented alone or in conjunction with another protein (for example CD14) [ 13], and the relatively high frequency of polymorphism observed in Tlr4 may be viewed as a consequence of the protective effect rendered by LPS recognition and the variability of LPS structure.
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