Words similar to preprotein

Example sentences for: preprotein

How can you use “preprotein” in a sentence? Here are some example sentences to help you improve your vocabulary:

SecA targets the preprotein to the membranous translocase complex composed of SecY, SecE, SecG, SecD, SecF, and YajC.
SecB binds portions of the mature secretory protein [ 14 15 16 17 18 ] , and SecA would bind to the SecB-precursor complex by virtue of its ability to bind SecB [ 19 20 ] as well as the preprotein [ 21 22 23 ] . Thus, SecA-mediated targeting of the preprotein to translocase would occur.
The signal sequence is crucial for efficient translocation; mutations in the signal sequence significantly reduce export of the preprotein and complete deletions of the signal sequence eliminate essentially all export [ 5 6 7 8 ] . Selection for extragenic suppressors of such export defective preproteins led to the identification of the prl alleles of secY ( prlA ), secE ( prlG ), secA ( prlD ), and more recently secG ( prlH ) [ 6 9 10 11 ] . Early hypotheses predicted that the Prl suppressors function by expanded or altered interactions with signal sequences, facilitating recognition of mutant as well as wild type signal sequences [ 6 ] .
Both SecB and the preprotein provide binding sites for SecA, a peripheral membrane ATPase.
Export of many, but not all, secretory proteins is dependent on interaction with SecB, a cytoplasmic chaperone that maintains the preprotein in a loosely folded conformation competent for translocation.