Words similar to preovulatory
Example sentences for: preovulatory
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However, in porcine preovulatory ovaries (late follicular phase), which contain numerous preovulatory follicles but no luteal tissue, very strong LHR immunoreactivity was also detected (lane 3, Fig.
Yet, cell surface staining was observed only on classic LH/CG targets, granulosa and theca cells of preovulatory follicles and mature luteal cells, but also in the vaginal epithelium.
The quantity of LH secreted by the anterior pituitary gland is the outcome of an interaction between the amount of hypothalamic GnRH secretion and the level of gonadotrope responsiveness to GnRH [ 7 ] . Quantitatively, gonadotrope responsiveness is more important than the level of GnRH secretion; for example, during the estrogen-stimulated preovulatory surge of LH secretion in the rat there is a 5-fold increase in GnRH secretion but a 50-fold increase in LH secretion [ 7 ] . Moreover, a quantity of GnRH that will evoke a normal preovulatory LH surge during the period preceding ovulation will induce only a small increase in LH secretion at other stages of the estrous cycle [ 7 ] . Similarly, termination of the preovulatory LH surge appears to be due to desensitization of the gonadotrope to GnRH action; in the sheep, a decrease in LH secretion precedes the decrease in GnRH secretion [ 41 ] , whereas in the rat, although the decrease in GnRH and LH secretion are co-incident [ 7 ] , there is evidence that the gonadotrope is already desensitized to GnRH [ 42 43 ] .
Finally, with regard to FSH action, FS has been shown to neutralize the bioactivity of the FSH inhibitor, BMP-15 [ 39 ] . It is possible, therefore, that the strong expression of FS by the DF may serve to modulate BMP-15 action such that sufficient FSH receptors are expressed in the GC to permit the development of a preovulatory follicle.
The mouse anti-rat LHR monoclonal antibody (mAb), clone 3B5, was developed against purified rat LHR [ 21 ] . The antibody showed immunoreactivity with rat granulosa cells of mature (preovulatory) follicles, ovarian thecal and interstitial cells, granulosa-lutein cells of developing, mature and regressing CL, and with testicular Leydig cells, and no reactivity with rat kidneys [ 22 ] . During the last ten years, affinity purified 3B5 antibody has been used in several immunohistochemical studies [ 23 24 25 26 ] . To our knowledge, however, no analysis of the 3B5 antibody by western blot has been reported.
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