Words similar to preovulatory
Example sentences for: preovulatory
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In porcine ovaries, LHR expression was detected in granulosa and theca cells of preovulatory follicles, but not in granulosa lutein cells of the mature CL [ 27 ] . In human ovaries, LHR expression was also detected in granulosa and theca cells of preovulatory follicles, but mature CL showed strong expression in luteal cells, which disappeared during luteal regression.
Porcine preovulatory follicles showed distinct LHR staining of theca interna, lack of LHR expression in vascular layer under the follicular membrane, and transition of granular cytoplasmic to surface LHR immunoreactivity in granulosa cells (Fig.
The quantity of LH secreted by the anterior pituitary gland is the outcome of an interaction between the amount of hypothalamic GnRH secretion and the level of gonadotrope responsiveness to GnRH [ 7 ] . Quantitatively, gonadotrope responsiveness is more important than the level of GnRH secretion; for example, during the estrogen-stimulated preovulatory surge of LH secretion in the rat there is a 5-fold increase in GnRH secretion but a 50-fold increase in LH secretion [ 7 ] . Moreover, a quantity of GnRH that will evoke a normal preovulatory LH surge during the period preceding ovulation will induce only a small increase in LH secretion at other stages of the estrous cycle [ 7 ] . Similarly, termination of the preovulatory LH surge appears to be due to desensitization of the gonadotrope to GnRH action; in the sheep, a decrease in LH secretion precedes the decrease in GnRH secretion [ 41 ] , whereas in the rat, although the decrease in GnRH and LH secretion are co-incident [ 7 ] , there is evidence that the gonadotrope is already desensitized to GnRH [ 42 43 ] .
Because folliculogenesis in the murine proceeds to the preovulatory stage in the absence of BMP-6 [ 30 ] , BMP-15 [ 15 ] , and BMPR-IB [ 31 ] , one can assume that the marked increases in these regulatory molecules are not essential for the development of a second layer of GC.
In other words, cells lacking surface LHR may not be influenced by temporary increase of LH production during the preovulatory period of the ovarian cycle due to the "cell membrane LHR barrier," and the LH effect is probably also prevented by the "vascular LHR barrier."
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