Words similar to preovulatory
Example sentences for: preovulatory
How can you use “preovulatory” in a sentence? Here are some example sentences to help you improve your vocabulary:
Because folliculogenesis in the murine proceeds to the preovulatory stage in the absence of BMP-6 [ 30 ] , BMP-15 [ 15 ] , and BMPR-IB [ 31 ] , one can assume that the marked increases in these regulatory molecules are not essential for the development of a second layer of GC.
Trophoblast cells are usually separated and grown in media containing phenol red (PhR) [ 35 ] . Phenol red is a weak estrogen with apparent biological effects, and the ERα binding affinity in Dulbecco's Modified Eagle's Medium (DMEM) is equivalent to levels of E2 as high as 0.45 nM [ 36 ] . Although relatively low when compared to the E2 levels in pregnancy, this estrogenic binding affinity of PhR is close to that of E2 during the preovulatory peak [ 4 5 ] . Therefore, we included studies with PhR+, PhR-/E2- and PhR-/E2+ media in order to determine the effect of estrogens on differentiation of cultured trophoblast cells (syncytium formation) derived from normal and abnormal placental types.
Lee et al [ 33] showed that progesterone interacted with P-gp, inducing its expression in the granulose cell in preovulatory follicles to modulate steroid efflux.
Finally, with regard to FSH action, FS has been shown to neutralize the bioactivity of the FSH inhibitor, BMP-15 [ 39 ] . It is possible, therefore, that the strong expression of FS by the DF may serve to modulate BMP-15 action such that sufficient FSH receptors are expressed in the GC to permit the development of a preovulatory follicle.
The quantity of LH secreted by the anterior pituitary gland is the outcome of an interaction between the amount of hypothalamic GnRH secretion and the level of gonadotrope responsiveness to GnRH [ 7 ] . Quantitatively, gonadotrope responsiveness is more important than the level of GnRH secretion; for example, during the estrogen-stimulated preovulatory surge of LH secretion in the rat there is a 5-fold increase in GnRH secretion but a 50-fold increase in LH secretion [ 7 ] . Moreover, a quantity of GnRH that will evoke a normal preovulatory LH surge during the period preceding ovulation will induce only a small increase in LH secretion at other stages of the estrous cycle [ 7 ] . Similarly, termination of the preovulatory LH surge appears to be due to desensitization of the gonadotrope to GnRH action; in the sheep, a decrease in LH secretion precedes the decrease in GnRH secretion [ 41 ] , whereas in the rat, although the decrease in GnRH and LH secretion are co-incident [ 7 ] , there is evidence that the gonadotrope is already desensitized to GnRH [ 42 43 ] .
Loading...