Words similar to preneoplastic

Example sentences for: preneoplastic

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These findings are consistent with normal appearing, preneoplastic hepatocytes forming clonal masses in the liver because M6P/IGF2R haploid insufficiency affords them with a selective growth and/or survival advantage relative to normal hepatocytes [ 46 ] .
Since the focus of the present study was on TGF-β expression changes in the preneoplastic gland, staining of the tumors was not scored for the analysis, but in the two cases present, the staining did not differ significantly from that of the surrounding normal-appearing ducts (not shown).
These lesions are called precancers, premalignancies, preneoplastic lesions, incipient cancers, intraepithelial neoplasias, and preinvasive cancers.
Analysis of X-chromosome inactivation in female patients with multiple head and neck cancers shows that distinct tumors arise from regional clonal growths of phenotypically normal, mutated preneoplastic cells [ 3 4 5 ] , a phenomenon similar to that also observed in liver cancer patients with cirrhosis [ 6 ] . Long-term smoking and alcohol abuse are strongly associated with these clonal growths in the upper aerodigestive tract (reviewed in [ 7 ] ).
Human clinical material for biomarker analysis in primary chemoprevention studies is also likely to comprise normal and initiated, at-risk epithelium with some early preneoplastic changes, but without evidence of major neoplastic change.