Example sentences for: pregnenolone

How can you use “pregnenolone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Moreover, despite multiple sites of action, the drug's actions cannot be dismissed as non-specific, because 4-AP had no effects on either 3β-hydroxysteroid dehydrogenase (3β-HSD)-mediated conversion of pregnenolone to progesterone, or androgen (androstenedione, 5αDHT)-stimulated progesterone synthesis.

  • After 24 h the medium was replaced with serum-free medium containing either pregnenolone (1 μg/ml), androstenedione (100 μM), 5α-dihydrotestosterone (5α-DHT, 10 or 100 μM), or forskolin (5 μM) and IBMX (10 μM).

  • 4-AP had no significant effect on progesterone production by PCG-2 cultured in the presence of pregnenolone, androstenedione or 5α-DHT (Figure 4A).

  • The cross-reactivity with pregnenolone (500 ng/mL) was 0.30%.


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