Words similar to predispose
Example sentences for: predispose
How can you use “predispose” in a sentence? Here are some example sentences to help you improve your vocabulary:
The MATs are predicated upon the coordinated activities of the spindle checkpoint [ 16 17 ] , the anaphase-promoting complex (APC) or cyclosome [ 18 19 ] , the proteasome [ 20 21 ] , and the cohesion-complex proteins involved with chromosome cohesion and separation [ 22 23 24 ] . Alterations in the temporal sequence of these coordinated activities may potentially predispose cells to faulty chromosome segregation.
Another candidate for a factor that may be changing with age is susceptibility to viral infections, especially influenza, which may predispose to pneumococcal colonization [25] or disease [26,27].
Certainly not all the findings are surprising; some rare cancers are already known to be associated with particular genetic defects, and syndromes that predispose to multiple cancers have been described, for example, that of Hereditary Nonpolyposis Colorectal Cancer.
The association of inhaled particulate pollution and cigarette smoking with pulmonary disease, such as chronic obstructive pulmonary disease, is well documented [ 1 ] , but the specific early responses of lung epithelial cells to toxic substances in particulates - that predispose the cells to disease - have not been elucidated.
Based on studies involving compounds that alter microtubular kinetics and induce both cell-cycle delay and aneuploidy, several groups have proposed that temporal perturbations during mammalian oocyte maturation (OM) predispose oocytes to aneuploidy [ 3 4 5 6 ] . In addition to faulty microtubule kinetics, perturbations during OM may also stem from abnormal function of centrosomes, kinetochores, spindle checkpoints proteins, the anaphase-promoting complex (APC), the securin-separin-cohesion complex proteins, and the proteasome [ 7 ] .
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