Example sentences for: predispose

How can you use “predispose” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We propose that the loss or reduction of BRCA1 may predispose a cell population to neoplastic transformation by altering the balance between cell death and proliferation/survival, rendering it more sensitive to secondary genetic changes.

  • The association of inhaled particulate pollution and cigarette smoking with pulmonary disease, such as chronic obstructive pulmonary disease, is well documented [ 1 ] , but the specific early responses of lung epithelial cells to toxic substances in particulates - that predispose the cells to disease - have not been elucidated.

  • Another candidate for a factor that may be changing with age is susceptibility to viral infections, especially influenza, which may predispose to pneumococcal colonization [25] or disease [26,27].

  • Most simply, individual MHC alleles may be especially effective, or especially ineffective, at presenting antigens from particular infections, so that carrying one or two copies of a given MHC allele might predispose an infected individual to a more or less favorable disease outcome.

  • RSV infection in infancy cause severe bronchiolitis and pneumonia and may predispose children to the subsequent development of asthma, the most common chronic illness of childhood [ 1 ] . Many studies have indicated that chemokines can play an important role in the onset and severity of asthma and it has been shown that RSV infection of lung epithelial cells increases chemokine production, although the mechanisms involved are largely unknown [ 2 3 4 5 ] .


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