Example sentences for: preaggregation

How can you use “preaggregation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The uORFs are involved mechanistically in bringing about enhanced translation initiation under conditions that otherwise favor a general decrease in translation initiation [ 25 ] . Within the 5' UTR of countin mRNA, we find uORFs similar in number and in arrangement to those of GCN4 mRNA, the major mRNA regulated by yeast GCN2 [ 25 ] . Thus, we suggest that countin mRNA, and probably other as yet identified mRNAs, are translationally upregulated when IfkA phosphorylates eIF2α during the preaggregation period, or from 1 to 7 hours after the onset of development.

  • These findings imply that IfkA is responsible for phosphorylating eIF2α during the preaggregation period.

  • In summary, the findings suggest that IfkA is an eIF2α kinase of Dictyostelium that normally phosphorylates eIF2α from 1 to 7 hours after the onset of development, or during the preaggregation phase.

  • Earlier than normal aggregation and cAMP pulsing also result from a lack of IfkA activity during preaggregation, and we postulate that this is due to the production and secretion of an as yet unidentified factor in early developing ifkA null cells.


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