Words similar to preaggregation
Example sentences for: preaggregation
How can you use “preaggregation” in a sentence? Here are some example sentences to help you improve your vocabulary:
The uORFs are involved mechanistically in bringing about enhanced translation initiation under conditions that otherwise favor a general decrease in translation initiation [ 25 ] . Within the 5' UTR of countin mRNA, we find uORFs similar in number and in arrangement to those of GCN4 mRNA, the major mRNA regulated by yeast GCN2 [ 25 ] . Thus, we suggest that countin mRNA, and probably other as yet identified mRNAs, are translationally upregulated when IfkA phosphorylates eIF2α during the preaggregation period, or from 1 to 7 hours after the onset of development.
In summary, the findings suggest that IfkA is an eIF2α kinase of Dictyostelium that normally phosphorylates eIF2α from 1 to 7 hours after the onset of development, or during the preaggregation phase.
Earlier than normal aggregation and cAMP pulsing also result from a lack of IfkA activity during preaggregation, and we postulate that this is due to the production and secretion of an as yet unidentified factor in early developing ifkA null cells.
These findings imply that IfkA is responsible for phosphorylating eIF2α during the preaggregation period.