Words similar to ppar
Example sentences for: ppar
How can you use “ppar” in a sentence? Here are some example sentences to help you improve your vocabulary:
It was reported that PPAR activation could down-regulate the activity of AP-1 by interfering with the functions of c-jun [ 36 37 ] . Therefore, the following set of experiments was designed to test if PPAR activation could reduce c-jun activation in 25-OH-cholesterol treated microglia.
PPAR agonists reduced the 25-OH-cholesterol induced c-jun activation and attenuated the cytotoxicity.
Based on the observations that: 1. cholesterol oxides cause PCD but the involvement of MAP kinases remains to be investigated; 2. PPARs are important in atherosclerosis but the effect of PPAR activation on cholesterol oxide induced PCD has not been determined, this study was designed to test if a dysregulation of MAP kinases was associated with the cholesterol oxide induced PCD, and to determine if PPAR activation could modulate the cholesterol oxide induced PCD.
Development of PPAR agonists that retain the antiatherogenic activity but dismiss the proatherogenic activities will be of great value [ 26 ] .
Cells were treated with 5 μM 25-OH-cholesterol together with PPAR agonists to be tested for 2 days, then the viability of each treatment was determined.
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