Example sentences for: ppar

How can you use “ppar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A recent study examined effects of PPARα-specific induction in murine livers using cDNA microarrays [ 30 ] . Despite the different strain of mice examined (C57BL/6J) and the different genomic technology utilized for the examination of differentially expressed genes (cDNA microarrays), several genes were found differentially regulated in both experiments, indicating that the PPAR agonist and LC-PUFA affect gene expression through similar pathways.

  • PPAR agonists attenuate cholesterol oxide induced cytotoxicity in microglia

  • PPARα is the predominant PPAR subtype expressed in liver, as confirmed presently.

  • Similar protective roles of PPAR agonists have been shown in other nervous tissues.

  • A number of RXR heterodimer complexes have been categorized as either permissive or non-permissive based on their responses to RXR ligands [ 1 ] . Although there are some reported discrepancies, the PPAR, FXR and NGF-IB/NURR1 complexes are generally considered permissive, while the non-permissive group includes the RAR, TR and VDR complexes (see [ 2 3 4 5 6 7 ] ). In the permissive complexes, coactivators can presumably bind to the AF-2 surface of both partners and binding to the RXR partner is stimulated by rexinoid agonists.


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