Example sentences for: ppar

How can you use “ppar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In spite of dramatic differences in the expression of a variety of PPAR-responsive genes, PPAR gene expression itself was quite constant in all mice analyzed, as previously reported [ 31 ] . This constancy of PPAR expression indicates that differences in the transcription of genes containing a PPRE are likely due to the direct activation of PPARs.

  • Cells were treated with 5 μM 25-OH-cholesterol together with these PPAR agonists for 12 hours, then processed for Western blot analyses.

  • A number of RXR heterodimer complexes have been categorized as either permissive or non-permissive based on their responses to RXR ligands [ 1 ] . Although there are some reported discrepancies, the PPAR, FXR and NGF-IB/NURR1 complexes are generally considered permissive, while the non-permissive group includes the RAR, TR and VDR complexes (see [ 2 3 4 5 6 7 ] ). In the permissive complexes, coactivators can presumably bind to the AF-2 surface of both partners and binding to the RXR partner is stimulated by rexinoid agonists.

  • PPAR agonists reduced the 25-OH-cholesterol induced c-jun activation and attenuated the cytotoxicity.

  • PPAR agonists attenuate cholesterol oxide induced cytotoxicity in microglia


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