Example sentences for: ppar

How can you use “ppar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Results indicated that while 25-OH-cholesterol induced the expression of c-jun and phospho-c-jun, these PPAR agonists reduced the expression to various degrees.

  • Given the suggestion that an up-regulation of c-jun is a cause of PCD [ 15 16 ] , a reduction in c-jun activation by PPAR agonists should attenuate 25-OH-cholesterol induced cytotoxicity.

  • Similar protective roles of PPAR agonists have been shown in other nervous tissues.

  • Although dietary LC-PUFA activated numerous transcriptional factors in both liver and hippocampus, it is a noteworthy difference that the transcriptional signatures for PPAR, SREBP, and HNF could not be detected in the hippocampal dataset.

  • Potential mechanisms for altered adipocyte function include, direct binding to PPARgamma or inhibition of transcription of PPARgamma promoter [ 37 ] . The lipodystrophy syndrome may be a result of the inhibition of 2 proteins involved in lipid metabolism that have significant homology to the catalytic site of HIV proteases; namely cytoplasmic retinoic acid binding protein type 1 and low density lipoprotein-receptor-related protein [ 38 ] . An additional mechanism of PPAR down-regulation may be related to Tat expression in latent cells.


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