Example sentences for: potently

How can you use “potently” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • TNFα rapidly and potently activates Rel A and p50 subunits of NF-κB through a kinase-mediated phosphorylation cascade involving a high molecular mass signaling complex called the IKK complex [ 56 ] . TNFα activation of the multiprotein IKK complex results in the serine phorsphorylation of I-κB and the subsequent activation of NF-κB [ 57 ] .

  • The idea of enlisting the immune system to fight cancer has been around for a long time, and has led to the development of various cancer vaccines designed to alert the immune system to the presence of a tumor and to induce a response that, selectively and potently, will eliminate tumor cells.

  • A 24-hour exposure to IFN-γ was sufficient to potently and irreversibly inhibit osteoclastogenesis in the presence of maximal doses of RANKL (Fig.

  • Cytokines potently induce activation and differentiation of target cells in a tightly regulated temporal fashion during immune responses [ 34].

  • Malignant tumor cells frequently show deregulation and hyperactivation of signalling pathways, one of which is represented by the TGFβ signal transduction pathway [ 1 ] . TGFβ has been shown to potently inhibit proliferation of most epithelial, endothelial and hematopoietic cells [ 2 ] . However, during tumor progression malignant cells may become refractory to TGFβ-mediated cell cycle arrest.


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