Words similar to potency
Example sentences for: potency
How can you use “potency” in a sentence? Here are some example sentences to help you improve your vocabulary:
There is a very tight relationship between the potency of activation domains and their stability [ [ 35 36 37 38 ] ]. Activation domains and sequences required for degradation overlap and mutations in the VP16 activation domain which impair its function result in enhanced protein stability [ 35].
These results strongly support the model, initially hypothesized for cyclopamine [ 11 ] , that the reduced potency observed for Hh antagonists on Smo act-expressing cells is directly due to a reduced affinity of the antagonist for the mutated Smo protein.
The potency of IFN-γ as a macrophage activator and osteoclast inhibitor suggests a prominent role for T cells and/or NK cells in the regulation of bone resorption, as these cells constitute the major source of IFN-γ [ 18 ] . A link between activated T cells and osteoclast inhibition by IFN-γ has been highlighted in a report by Takayanagi et al ., providing the first in vivo evidence that the immune system may influence osteoclastogenesis [ 38 ] . Interestingly, other groups have demonstrated that activated T cells induce osteoclastogenesis via upregulation of surface RANKL, presenting a dilemma regarding the role of activated T cells in osteoclastogenesis [ 20 40 45 ] .
The rank order of affinity agrees with the rank order of potency of these ligands in inhibiting forskolin-stimulated cAMP production.
This difference in potency appears to be a characteristic of the receptor protein itself, because the cellular environment in which a particular subtype is expressed does not affect the potency of norepinephrine to produce down-regulation.
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