Words similar to postnatal
Example sentences for: postnatal
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Mutations in TMC1 are responsible for the autosomal dominant human hearing disorder DFNA36 and for the recessive deafness DFNB7/11 [ 5 ] ; the corresponding murine gene Tmc1 also causes deafness in the mutant mouse strains Beethoven ( Bth ) and deafness ( dn ) [ 6 ] . Bth / Bth mice display altered potassium currents in early postnatal cochlear hair cells, in particular Ik,n and Ik,f currents appear to be depressed [ 10 ] . This observation led to the hypothesis that Tmc1 may participate directly or indirectly in regulating the permeability of potassium channels [ 10 ] . Because of the high level of conservation of the amino acid sequences among the eight mammalian TMC proteins (Figure 1, Additional file 1), we speculate that other TMC proteins may as well be modifiers of ion channels or transporters.
Much of this information comes from animal cells and embryos, but the addition of BMP2 to cultured postnatal human bone marrow `preosteoblastic' cells in the presence of β-glycerophosphate and ascorbic acid increases the gene message and protein production of AP, osteopontin, bone sialoprotein, osteocalcin, and α-1 collagen [ 33].
Sympathetic neuronal cultures were obtained by dissociating superior cervical ganglia from perinatal (21 day embryos to 1 day postnatal) Holtzman rats (Harlan Sprague-Dawley, Indianapolis), using previously described methods [ 13].
The expression of both Dazl1 and Dazap1 persisted throughout testes development, in both the prenatal and postnatal periods.
If BMP-5 is important in regulating dendritic growth in intact ganglia, its expression should correlate with periods of dendritic growth in vivo . In sympathetic ganglia, dendritic growth begins prenatally and maximal expansion of the dendritic arbor occurs during postnatal weeks 1 and 2 [ 47 48 ] . RT-PCR analyses of intact SCG indicate that cells of the SCG express BMP-5 transcripts from E20 through P7.
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