Example sentences for: positively-charged

How can you use “positively-charged” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As part of this role, the function of the highly extended D/E-rich domain in midasin could be to interact with positively-charged nuclear protein substrates in a manner analogous to the acidic regions of the nuclear transport GTPase Ran [ 51 ] , the nuclear transporter Tpr [ 52 ] , and the chromatin remodeling proteins of the SWI/SNF family [ 53 ] . However, there are alternative possibilities that need to be considered.

  • For example, oligodeoxyribonucleotide probes can be covalently attached to a surface [ 10 ] , synthesized in situ [ 11 12 13 ] , or retained via electrostatic interactions with a positively charged surface [ 14 ] . A recent study examining the effect of mismatches along the length of in situ synthesized 60 mer oligodeoxyribonucleotides demonstrated a lack of an effect of mismatches for the first ten to fifteen bases at the 3' (surface) end of the oligodeoxyribonucleotide, suggesting that these bases may not be accessible during the hybridization reaction [ 12 ] . Other problems may exist when oligodeoxyribonucleotides are adsorbed to a positively-charged surface.

  • The protected fragments of the probes were resolved in 5% denaturing polyacrylamide gel followed by blotting to a positively-charged nylon membrane.

  • These negatively-charged EGF-like modules of LTBP-3 may interact efficiently with the positively-charged heparin-binding domain of both the membrane-bound and soluble forms of HB-EGF.


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