Example sentences for: polysomes

How can you use “polysomes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This apparent preference for 6His-HA-PP1α RNA association with polysomes suggest that autoregulation takes place, at least in part, at the translational level.

  • . IfkA activation at these times results is a reduction in overall protein synthesis initiation as indicated by the secondary shift of polysomes to ribosomes.

  • A very early event marking the initiation of development is a substantial reduction in overall translation initiation and a concomitant major shift of ribosomes from mRNA-associated ribosomes (polysomes) to free ribosomes [ 22 23 ] . The percentage of mRNA associated with polysomes drops from about 80-90% in growing cells to 50-60% within several minutes of the removal of the food source.

  • After 2 and 4 hours of development, cells were collected into polysome buffer (HMK-NP40 plus cycloheximide to stabilize the polysomes).

  • Early studies indicated that depletion of amino acids and not other nutrients is essential for initiation of development [ 19 20 21 ] . Upon amino acid starvation, among other events there is a substantial decrease in the rate of initiation of protein synthesis, resulting in a reduction in size and amount of polysomes and accumulation of free ribosomes [ 19 22 23 ] . It is believed that the decrease in protein synthesis in response to starvation occurs post-transcriptionally, since adding back amino acids rapidly restores protein synthesis and does not require new mRNA synthesis [ 22 ] .


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