Words similar to polysomes

Example sentences for: polysomes

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A decrease in polysomes of about 15 % and an equivalent increase in free ribosomes was observed when the polysome profile of Ax4 cells developed for 2 or 4 hours was compared to the profile from BS153 cells developed for the same time or to the profile from Ax4 cells developed for only 10 minutes.
Early studies indicated that depletion of amino acids and not other nutrients is essential for initiation of development [ 19 20 21 ] . Upon amino acid starvation, among other events there is a substantial decrease in the rate of initiation of protein synthesis, resulting in a reduction in size and amount of polysomes and accumulation of free ribosomes [ 19 22 23 ] . It is believed that the decrease in protein synthesis in response to starvation occurs post-transcriptionally, since adding back amino acids rapidly restores protein synthesis and does not require new mRNA synthesis [ 22 ] .
. IfkA activation at these times results is a reduction in overall protein synthesis initiation as indicated by the secondary shift of polysomes to ribosomes.
As described above, bulk mRNA undergoes a secondary shift from polysomes to free ribosomes in Ax4 cells, and this shift was not seen in BS153 cells as it is dependent upon eIF2α phosphorylation by IfkA.
This apparent preference for 6His-HA-PP1α RNA association with polysomes suggest that autoregulation takes place, at least in part, at the translational level.