Words similar to polyposis
Example sentences for: polyposis
How can you use “polyposis” in a sentence? Here are some example sentences to help you improve your vocabulary:
The study revealed that treatment of Min /+ mice with established polyposis with aspirin for 4 weeks produce no appreciable therapeutic effect.
Polyposis in the Min /+ mouse differs slightly from the human condition of FAP.
This is evident when one evaluates the concentrations required to achieve anticancer, cytoprotective actions in vitro [ 19 21 25 26 27 ] . More recently in the Apc minmouse model of familial adenomatous polyposis, a condition with a massive induction of polyps in the gastrointestinal tract, green tea extracts reduced polyp load and potentiated the effects of sulindac, a cyclo-oxygenase inhibitor used to treat gastrointestinal cancer [ 32 ] . This further affirms the potential of this strategy in managing disorders characterized by epithelial cell death and transformation.
To date no studies or case reports have examined the use of aspirin in the treatment of FAP, although various clinical trials are under way [ 33 ] . In accordance with the above data, studies conducted in animals have always employed a prevention strategy as well [ 4 7 9 ] . To our knowledge, this is the first study to examine the therapeutic potential of aspirin in a rodent model of colon carcinogenesis, in particular, the Min /+ murine model of polyposis.
We therefore wanted to determine if aspirin is able to reduce the number and size of adenomas in Min /+ mice with established polyposis.