Example sentences for: polyposis

How can you use “polyposis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The study revealed that treatment of Min /+ mice with established polyposis with aspirin for 4 weeks produce no appreciable therapeutic effect.

  • Polyposis in the Min /+ mouse differs slightly from the human condition of FAP.

  • This is evident when one evaluates the concentrations required to achieve anticancer, cytoprotective actions in vitro [ 19 21 25 26 27 ] . More recently in the Apc minmouse model of familial adenomatous polyposis, a condition with a massive induction of polyps in the gastrointestinal tract, green tea extracts reduced polyp load and potentiated the effects of sulindac, a cyclo-oxygenase inhibitor used to treat gastrointestinal cancer [ 32 ] . This further affirms the potential of this strategy in managing disorders characterized by epithelial cell death and transformation.

  • To date no studies or case reports have examined the use of aspirin in the treatment of FAP, although various clinical trials are under way [ 33 ] . In accordance with the above data, studies conducted in animals have always employed a prevention strategy as well [ 4 7 9 ] . To our knowledge, this is the first study to examine the therapeutic potential of aspirin in a rodent model of colon carcinogenesis, in particular, the Min /+ murine model of polyposis.

  • We therefore wanted to determine if aspirin is able to reduce the number and size of adenomas in Min /+ mice with established polyposis.


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