Words similar to polyphenols
Example sentences for: polyphenols
How can you use “polyphenols” in a sentence? Here are some example sentences to help you improve your vocabulary:
The team has also quickly broadened its horizons and is already testing the polyphenols on mouse disease models.
Recently, both green tea and cat's claw have been reported to reduce the expression of inflammatory genes; responses that are linked to apoptosis and proliferation [ 23 24 25 26 27 ] . Indeed, cat's claw has been described as a potent inhibitor of the transcription factor NF-κB activation, preventing the expression of TNFα and inducible nitric oxide synthase [ 23 24 ] . These immune/inflammatory products are associated with gastritis and epithelial cell death [ 5 6 7 13 ] and hence cat's claw may have utility in limiting gut inflammation [ 23 ] . Indeed, this matches its ethnomedical use in South America where it is used to treat gastritis and other forms of chronic inflammation like arthritis [ 28 ] . Green tea, and its constituent polyphenols, has been associated with reduced expression of inflammatory genes and signal transduction processes leading to cell death [ 21 25 26 27 ] .
Several pharmacological properties of plants reputed to be snakebite antidotes include antimyotoxic, antihaemorrhagic, analgesic, and antiedematogenic, blockage of cutaneous and intraperitoneal capillary permeability activity caused by the venom and protection from its lethality [ 38 ] . A more direct anti-venom activity would involve complexation of the compounds with venom constituents thus rendering them unable to act on receptors; or to act by competitive blocking of the receptors [ 11 ] . Phenolic compounds especially complex polyphenols like some tannins can bind with proteins [ 42 ] . Alternatively, the catecholamines released as a result of venom-receptor interaction may be antagonised or metabolised more quickly [ 11 ] .
In contrast, a recent study in Japan indicated that the consumption of green tea was not associated with either a reduction or an increase in gastric cancer rates [ 31 ] . This raises concern as to the ability of polyphenols derived from green tea to afford protection from mutagenic substances or limit the progression of established cancer.
Not only did they find “a whole collection of related polyphenols that activate ‘Sir-2 from humans,’ … but we put them onto yeast, justbeing the simplest model, and amazingly [they] did what we were hoping [they] would do,” recalls Sinclair.
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