Words similar to polychlorinated
Example sentences for: polychlorinated
How can you use “polychlorinated” in a sentence? Here are some example sentences to help you improve your vocabulary:
PCB, polychlorinated biphenyls
Epidemics of overt toxicity following widespread environmental contamination from commercial toxins heralded the discovery of children's enhanced vulnerability to lead, methyl mercury, polychlorinated biphenyls (PCBs), and tobacco [1,2,3,4,5] (Box 1).
On one hand, there is increasing and rather convincing observational and experimental data underscoring the beneficial effects of marine fish consumption on fetal growth and gestation [ 1 2 3 ] . On the other hand, consumption of environmentally contaminated fish has been associated with decrements in gestation and birth weight in some studies [ 4 5 6 ] . Animal evidence suggests that Rhesus monkeys, rats and mice exposed to polychlorinated biphenyls (PCBs) in utero have reductions in length of gestation and growth [ 7 8 9 ] . The results from accidental environmental exposures also report adverse effects on birth size and ectodermal manifestations among fetuses to various polyhalogenated hydrocarbons [ 10 11 ] . One occupational study has reported a negative relation between PCB exposure and infant birth weight, which no longer remained significant after adjusting for gestation and other variables related to birth weight [ 12 ] . Results from a birth cohort study in the Faroe Islands, a community with a high intake of marine fish, whale meat and blubber, supported a relation between marine fatty acids and diminished birth weight for gestation, but the effects were not attributed to the mercury or PCB exposure [ 13 ] .
Contamination of the Great Lakes has led to the bioaccumulation of polychlorinated biphenyls (PCBs) in fish, particularly the larger predator species prized by sport-fishers [ 1 2 3 ] . These compounds are synthetic organochlorines (OC) that, along with dichlorodiphenyl-dichloroethene (DDE), comprise the bulk of OC residues found in human tissues [ 4 ] , and some of the highest body burdens of PCBs in humans are found among fish consumers [ 5 6 7 8 ] . Consumption of these contaminated Great Lakes fish has been associated with several adverse reproductive outcomes including shortened menstrual cycle [ 9 ] , reduced fecundability [ 10 11 ] , reduced neonatal size [ 12 ] , and neurologic disorders [ 13 14 15 ] .
The specific PCB congeners to which people were exposed following the Yucheng and Yusho incidents may have been somewhat different from those found in Great Lakes fish and fish consumers [ 3 49 51 54 55 56 ] , and, unlike exposure to PCBs from Great Lakes fish, the Yucheng and Yusho incidents also involved significant exposure to polychlorinated dibenzofurans (PCDFs) as a result of heating the contaminated rice oil for cooking [ 49 51 54 ] . Whether these differences could explain the differences in sex ratio findings between the Yusho and Yu-cheng incidents and our findings is not clear.
Loading...