Example sentences for: pointes

How can you use “pointes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It was therefore impossible to consider the influence of QTc prolongation on the occurrence of critical cardiac arrhythmias such as torsades de pointes.

  • Hypokalemia and many types of electrocardiographic (ECG) abnormality are observed during the acute phase of subarachnoid hemorrhage (SAH) [ 1 2 3 ] . Among ECG abnormalities, a prolongation of the QT interval, especially when associated with hypokalemia, deserves particular attention because it is frequently observed in those patients who develop life-threatening ventricular arrhythmias such as tor-sades de pointes [ 1 2 4 ] . However, the pathogeneses of these abnormalities during the acute phase of SAH have not yet been fully investigated.

  • Furthermore, recent evidence suggested that women are more prone than men to develop torsades de pointes during administration of cardiovascular drugs that prolong cardiac repolarization [ 9 16 ] .

  • Cardiac conduction disturbance has also been recognized in the mitochondrial cytopathy, Kearns-Sayre syndrome (Mendelian inheritance in Man database *530000), characterized as progressive external ophthalmoplegia and retinopathy [ 16 ] . Clinical manifestations of cardiac disease occur in 57% of patients with Kearns-Sayre syndrome [ 17 ] . The complete AV block in Kearns-Sayre syndrome may also be associated less commonly with ventricular tachycardia, torsade de pointes and ventricular fibrillation as the ultimate and often fatal stage of the condition [ 18 ] . However, to our knowledge, ventricular tachycardia as a presenting feature has not been described in the context of mitochondrial cytopathies in the neonatal period.

  • However, little is known about the mechanism responsible for these sex related differences in the QTc interval or in the occurrence of torsades de pointes.


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