Example sentences for: pleiotropic

How can you use “pleiotropic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Classic methods of identifying genes involved in neural function include behavioral screening of mutagenized flies, then rescreening candidate lines for pleiotropic effects due to developmental defects.

  • Recombinant human interleukin-11 (rhIL-11) is a pleiotropic cytokine that regulates the growth and development of hematopoietic stem cells and decreases the proinflammatory mediators of cytokine and nitric oxide production [ 1].

  • The abnormal genetic architecture of inbred strains and the fixation of multiple alleles that affect fitness will almost inevitably produce unusual pleiotropic and epistatic effects on a range of complex traits.

  • mod(mdg4) has been implicated in a range of cellular and developmental processes, including chromatin insulator functions [ 52] and apoptosis [ 53], and it has been suggested that its many different isoforms underlie the pleiotropic nature of this gene [ 49].

  • The single-gene diageotropica (dgt) mutant of tomato ( Lycopersicon esculentum ) displays a pleiotropic phenotype that includes reduced auxin sensitivity [ 13].

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