Example sentences for: pleiotropic

How can you use “pleiotropic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To separate the specific role of hypophosphorylated RARα from the pleiotropic effects of the ligand, we expressed a non-phosphorylatable S77A mutant protein in human cancer cells.

  • The acid form, retinoic acid, is a pleiotropic hormone which regulates gene expression in embryonic development, epithelial cell differentiation, hematopoeisis, and tumor cell formation.

  • So maybe there is an accidental, pleiotropic connection between madness and mathematics.

  • Obviously, mutations in mt-tRNA, mt-rRNA and proteins that affect mitochondrial gene expression will also potentially have pleiotropic effects.

  • The abnormal genetic architecture of inbred strains and the fixation of multiple alleles that affect fitness will almost inevitably produce unusual pleiotropic and epistatic effects on a range of complex traits.


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