Example sentences for: pleiotropic

How can you use “pleiotropic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Obviously, mutations in mt-tRNA, mt-rRNA and proteins that affect mitochondrial gene expression will also potentially have pleiotropic effects.

  • SPARC-null mice and their cells should provide a useful system to investigate how a matricellular protein regulates pleiotropic functions through cell migration and how its absence alters biological processes.

  • Classic methods of identifying genes involved in neural function include behavioral screening of mutagenized flies, then rescreening candidate lines for pleiotropic effects due to developmental defects.

  • Recombinant human interleukin-11 (rhIL-11) is a pleiotropic cytokine that regulates the growth and development of hematopoietic stem cells and decreases the proinflammatory mediators of cytokine and nitric oxide production [ 1].

  • The Chr 10 locus clearly has pleiotropic effects on the CNS, but its effect on the striatum is more intense.


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