Example sentences for: pleiotropic

How can you use “pleiotropic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • SPARC-null mice and their cells should provide a useful system to investigate how a matricellular protein regulates pleiotropic functions through cell migration and how its absence alters biological processes.

  • In general, these competitions in novel environments suggest that mutations that were beneficial in the selective environment may sometimes have positive pleiotropic effects.

  • To separate the specific role of hypophosphorylated RARα from the pleiotropic effects of the ligand, we expressed a non-phosphorylatable S77A mutant protein in human cancer cells.

  • The single-gene diageotropica (dgt) mutant of tomato ( Lycopersicon esculentum ) displays a pleiotropic phenotype that includes reduced auxin sensitivity [ 13].

  • The abnormal genetic architecture of inbred strains and the fixation of multiple alleles that affect fitness will almost inevitably produce unusual pleiotropic and epistatic effects on a range of complex traits.


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