Example sentences for: pleckstrin

How can you use “pleckstrin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Another putative protein (GI number 15228210, locus id At3g47660) has a previously undetected domain at the amino terminus which resembles the structure of the pleckstrin homology (PH) domain from phospholipase C delta (PDB 1mai) (C prediction).

  • However, in contrast to the other Tec family members, Rlk lacks a pleckstrin homology domain.

  • To investigate whether binding to PIP 2 may be important for Boi1 function, we sought to make mutant versions of Boi1-PH that are defective in the ability to bind PIP 2 . As a guide for designing such mutants, we used information about one of the PH domains from pleckstrin.

  • These include SH3 domains (Src homology 3 domains, that bind to target proteins), MYTH4 (a domain of unknown function found in a few classes of myosins), a zinc-binding domain, a pleckstrin homology domain, FERM/talin (band 4.1/ezrin/radixin/moesin), GPA-rich domains and a protein kinase domain [ 8, 22, 26].

  • Thus, despite lacking a pleckstrin homology domain, Rlk is localized in RAFTs, is phosphorylated by Src family kinases, and may transduce signals downstream of Src family kinases during T cell activation.


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