Example sentences for: pleckstrin

How can you use “pleckstrin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • PH, pleckstrin homology; PI3K, phosphoinositide 3-Kinase; SH2, Src homology-2, SH3, Src homology-3; XLA, X-linked agammaglobulinemia; xid ; x-linked immunodeficiency; TCR, T cell receptor; sIgM, surface immunoglobulin M; (GAP), GTPase-Activating Protein; GST, Glutathione S-Transferase; SDS, Sodium Dodecyl Sulfate; PBS, phosphate buffered saline; NP40, Nonidet P-40; PAGE, polyacrylamide gel electrophoresis.

  • Figure 4shows those positions in the N-terminal PH domain of pleckstrin that have been implicated, based on NMR analysis, to contact PIP 2 [ 17 ] . Boi1's PH domain has identical or similar amino acids at most of the analogous positions (Fig.

  • Perhaps the most obvious of these differences is the lack of the pleckstrin homology domain in Rlk.

  • However, consistent with the lack of a pleckstrin homology domain, activation of Rlk is independent of PI3K activity [ 19].

  • In the inactive state, the Rho-binding domain and the pleckstrin homology domain form an autoinhibitory loop by binding and blocking the kinase domain at the N-terminus of the molecule.


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