Example sentences for: pleckstrin

How can you use “pleckstrin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, in contrast to the other Tec family members, Rlk lacks a pleckstrin homology domain.

  • However, consistent with the lack of a pleckstrin homology domain, activation of Rlk is independent of PI3K activity [ 19].

  • PH, pleckstrin homology; PI3K, phosphoinositide 3-Kinase; SH2, Src homology-2, SH3, Src homology-3; XLA, X-linked agammaglobulinemia; xid ; x-linked immunodeficiency; TCR, T cell receptor; sIgM, surface immunoglobulin M; (GAP), GTPase-Activating Protein; GST, Glutathione S-Transferase; SDS, Sodium Dodecyl Sulfate; PBS, phosphate buffered saline; NP40, Nonidet P-40; PAGE, polyacrylamide gel electrophoresis.

  • In addition to a COOH-terminal PTK domain, Btk has an NH 2 - terminal pleckstrin homology (PH) domain, a proline-rich Tec homology domain, a Src-homology 3 (SH3) domain and a Src-homology 2 (SH2) domain.

  • To investigate whether binding to PIP 2 may be important for Boi1 function, we sought to make mutant versions of Boi1-PH that are defective in the ability to bind PIP 2 . As a guide for designing such mutants, we used information about one of the PH domains from pleckstrin.


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