Words similar to pleckstrin
Example sentences for: pleckstrin
How can you use “pleckstrin” in a sentence? Here are some example sentences to help you improve your vocabulary:
PH, pleckstrin homology; PI3K, phosphoinositide 3-Kinase; SH2, Src homology-2, SH3, Src homology-3; XLA, X-linked agammaglobulinemia; xid ; x-linked immunodeficiency; TCR, T cell receptor; sIgM, surface immunoglobulin M; (GAP), GTPase-Activating Protein; GST, Glutathione S-Transferase; SDS, Sodium Dodecyl Sulfate; PBS, phosphate buffered saline; NP40, Nonidet P-40; PAGE, polyacrylamide gel electrophoresis.
To investigate whether binding to PIP 2 may be important for Boi1 function, we sought to make mutant versions of Boi1-PH that are defective in the ability to bind PIP 2 . As a guide for designing such mutants, we used information about one of the PH domains from pleckstrin.
In the inactive state, the Rho-binding domain and the pleckstrin homology domain form an autoinhibitory loop by binding and blocking the kinase domain at the N-terminus of the molecule.
These include SH3 domains (Src homology 3 domains, that bind to target proteins), MYTH4 (a domain of unknown function found in a few classes of myosins), a zinc-binding domain, a pleckstrin homology domain, FERM/talin (band 4.1/ezrin/radixin/moesin), GPA-rich domains and a protein kinase domain [ 8, 22, 26].
Another putative protein (GI number 15228210, locus id At3g47660) has a previously undetected domain at the amino terminus which resembles the structure of the pleckstrin homology (PH) domain from phospholipase C delta (PDB 1mai) (C prediction).