Example sentences for: plays

How can you use “plays” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The vast audience that attends the plays of Samuel Beckett or reads the poetry of John Ashbery is sadly neglected in our political process.

  • COX-2 is an inducible enzyme upregulated in inflammatory states [ 20 21 ] . Notably, many NSCLC and what have been characterized as "premalignant" lung lesions have been shown to constitutively express the COX-2 enzyme and produce prostaglandin E-2 (PGE-2), the primary product of the COX-2 pathway [ 22 23 24 25 26 ] . Importantly, PGE-2 production by tumor cells has been linked to tumor-induced immunosuppression in NSCLC [ 2 3 4 5 ] . PGE-2 has been shown to directly suppress T cell mediated immunity, the primary effector against tumor cells, at a variety of levels [ 2 3 4 5 6 7 ] . Further, PGE-2 has been shown to induce the IL10 in mononuclear cells [ 4 5 ] . IL10 is a prominent immunosuppressive cytokine that may have a dominant role in preventing innate antitumor responses in the NSCLC environment [ 2 3 4 5 ] , [ 8 9 10 11 12 13 14 15 16 17 18 19 ] . Among myriad suppressive effects on T cells and antigen presenting cells, IL10 is known to inhibit IL12 production [ 14 15 16 17 18 ] . IL12 plays a key role in the initiation and potentiation of cellular immune responses and alteration of the IL12 producing function in circulating mononuclear phagocytes may be a critical factor in suppressed T cell immunity to NSCLC [ 27 28 ] .

  • LcrG and LcrV physically interact in Y. pestis [ 4 ] , and that interaction plays a significant role in the regulation of Yops secretion [ 20 ] . LcrG and LcrV interact in a yeast two-hybrid assay [ 20 ] , therefore this technique was used to further investigate the region of LcrG required for its interaction with LcrV.

  • The clinical observation that sexual dimorphism plays a role in the immune response suggests that the endocrine system is an important factor for the development and maintenance of the response.

  • The hotel also plays host to Dolphin Quest, an encounter with one of man’s favorite animals.


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