Words similar to phytosterols
Example sentences for: phytosterols
How can you use “phytosterols” in a sentence? Here are some example sentences to help you improve your vocabulary:
Another formal possibility not excluded is that the Gly583Cys missense mutation may have no significance in the accumulation of phytosterols in WKY, SHR and SHRSP, and that the alteration in the 3' UTR or even the intronic changes reported above may be the causative 'mutations'.
Studies reported by different investigators have shown that a dietary intake of 10 % canola oil (as part of semi-purified diets) significantly shortened the life-span of SHRSP rats, with accumulation of phytosterols in plasma, red blood cells and tissues [ 15 17 18 19 21 22 ] . Lower red blood cell (RBC) membrane deformability, lower density of platelets, as well as a higher blood pressure were also observed, when compared to a SHRSP group fed with vegetable oils lower in phytosterols (10 % soybean oil vs. 10% canola oil).
Jatropha curcas latex is applied to external wounds in Perú and Indonesia [ 77 78 ] . The leaf bath is used for rash, bewitchment and poultices for sores in Trinidad [ 52 ] . Jatropha curcas leaf and bark contain glycosides, tannins, phytosterols, flavonoids and steroidal sapogenins [ 79 80 ] . The latex contains proteolytic enzymes and provides significant cicatrizant activity (wound healing) [ 78 ] . The sap inhibits growth of Candida albicans and Staphylococcus aureus [ 81 ] .
Studies have shown that the sitosterolemic patients hyperabsorb all sterols (cholesterol and phytosterols) and fail to excrete phytosterols into bile [ 3 4 5 6 7 ] . Positional mapping of the STSL locus to human chromosome 2p21 led to the identification of two genes, ATP binding cassette (ABC) half-transporters G5 and G8 that were mutated in affected individuals [ 8 9 10 11 12 ] . The protein products of these two genes (sterolin-1 and sterolin-2 respectively) are thought to form heterodimers to constitute a functional transporter, based primarily on the genetic evidence that affected individuals are either completely mutated in sterolin-1 or sterolin-2, but not both [ 12 ] . More recently, evidence from in vitro expression of these proteins has been presented that these two proteins co-immunoprecipitate, supporting this conclusion [ 13 ] . ABCG5 and ABCG8 appear to be present in all mammalian genomes examined to date and are highly conserved between species, indicating that these genes may have a similar function in other species.
ABCG5 and ABCG8 are two genes located adjacently in a head-to-head configuration on human chromosome 2p21, encoding for two half-transporters, sterolin 1 and sterolin 2 respectively [ 9 10 12 ] . Mutations in either of these genes causes sitosterolemia, characterized by hyperabsorption of phytosterols, reduced excretion of sterols into the bile and very elevated levels of plasma plant sterol levels.
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