Words similar to photoreceptor
Example sentences for: photoreceptor
How can you use “photoreceptor” in a sentence? Here are some example sentences to help you improve your vocabulary:
For example, levels of 4-HNE increased significantly in the vitreous of patients with proliferative vitreoretinopathy compared with controls [ 17 ] . Further, 4-HNE forms a stable adduct with rhodopsin in the photoreceptor, which may interfere with its functions [ 18 ] . 4-HNE even causes cataracts in cultured rat lens [ 19 20 ] . Whether oxidative stress on RPE can cause accumulation of cellular HNE-protein adducts remains unknown.
At some locations, however, there was retinal dysplasia or disorganization of photoreceptor position.
Retinal dysplasia is characterized by palisading outer retinal cells that surround a central lumen [ 57 ] . It occurs in mice with a variety of genetic defects and in some instances is associated with abnormalities of the retinal pigment epithelium [ 58 59 60 61 62 ] . Both during development and in adult life, the retinal pigment epithelium is critical to retinal function [ 63 ] . BMP2 and 4 may act as negative growth regulators in the retinal pigment epithelium [ 64 ] . It is possible that haploinsufficiency of BMP4 in the retinal pigment epithelium may be responsible for focal retinal dysplasia and displacement of photoreceptor nuclei.
The Seven in Absentia (SinA) protein was discovered in Drosophila as a mediator of photoreceptor development [ 29 ] . Subsequently, SinA was shown to participate in the ubiquitin/proteasome pathway [ 30 31 ] . The presence of a RING finger domain in the N-terminus of the mammalian homologue of SinA, "Siah", suggests it may be involved in targeting specific proteins for degradation in the proteasome as a ubiquitin ligase [ 32 ] . Two mammalian genes encoding Siah, Siah1 and 2, are known.
It induces neuronal differentiation in retinoblastoma cells, protects retina neurons (including photoreceptors) from death by apoptosis and other insults, and has a morphogenetic effect on photoreceptor cells [ 3 4 5 6 ] . It also has neurotrophic effects on neurons from the cerebellum, hippocampus and spinal cord [ 7 8 9 10 11 12 ] . In the intact retina, this factor is identified as a secreted protein associated by ionic interactions with the interphotoreceptor matrix [ 13 14 ] , where GAGs are the major polyanionic components.
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