Words similar to pfpp
Example sentences for: pfpp
How can you use “pfpp” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus, an in-depth study of PfPP1 and its interacting subunits may shed light on the regulation of the relevant pathways in this clinically important family of parasites.
Auto-inhibitory role of PfPP5 TPR: activation by polyunsaturated fatty acids
The gametogenesis was confirmed by the appearance of Pfg27, an early gamete-specific protein [ 30 ] . Having demonstrated that the monoclonal antibody was specific for PP1, we used it in an attempt to inhibit PfPP1 activity in vitro . At optimal concentrations, the antibody almost completely inhibited (90% inhibition) recombinant PfPP1 (including its Tyr phosphatase activity), and also inhibited the phosphatase activity of the P. falciparum extract by about 70% (data not shown).
This moderate OA-sensitivity further establishes the identity of PfPP5, since other PP5 enzymes also exhibit an IC 50 value for OA in the 4-6 nM range [ 18 ] . The ΔTPR mutant exhibited an essentially identical IC 50 (not shown), supporting the notion that the TPR domains do not play a direct role in the interaction with OA.
5B), correlating the antigenic reactivity of PfPP1 with its affinity for the toxin.