Words similar to peroxidation
Example sentences for: peroxidation
How can you use “peroxidation” in a sentence? Here are some example sentences to help you improve your vocabulary:
The results of cell culture and animal studies have shown that omega 3 polyunsaturated fatty acids (n-3 PUFAs) selectively killed cancer cells in vitro [ 1 ] . Furthermore, n-3 PUFAs incorporated into animal diets have reduced tumor growth rates in vivo [ 2 3 4 ] . The prevailing hypothesis for the reduction in tumor cell growth, in vitro or in vivo , by supplementing the diet with high levels of n-3 PUFAs has been that the incorporation of n-3 PUFAs into cell membranes of the tumor cells increased the susceptibility of the cells for lipid peroxidation and that the products of lipid peroxidation subsequently accumulated to cytostatic or cytotoxic levels [ 2 5 6 7 ] . It has also been reported that supplementing the diet of cancer xenograft bearing mice with n-3 PUFAs could increase the efficacy of edelfosine [ 8 ] , doxorubicin [ 9 ] , mitomycin [ 10 ] , cyclophosphomide and 5-fluorouracil [ 11 ] or irinotecan [ 12 ] against the tumor.
Peroxynitrite is a potent oxidant that can induce lipid peroxidation and as such may provide important insight.
Similarly, the concentration of NO can also augment [ 20, 21] or inhibit [ 22, 23] oxygen-radical mediated tissue damage and lipid peroxidation.
Lipid peroxidation products, such as 4-hydroxynonenal (4-HNE), have attracted considerable attention because of their potential involvement in aging and in a number of neuropathological conditions [ 16 ] . 4-HNE was implicated in the etiology of some pathological conditions in the eye.
These results indicate that n-3 PUFAs in the diet are incorporated in cell membranes, increasing the polyunsaturation of the membrane and increasing the susceptibility for lipid peroxidation.
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